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  5. ALDH7A1 Antibody (YA2034)

ALDH7A1 Antibody (YA2034)

Cat. No.: HY-P82289
COA
SDS
User Guide for Antibodies Technical Support

ALDH7A1 Antibody (YA2034) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ALDH7A1.

For research use only. We do not sell to patients.

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50 μL In-stock
100 μL In-stock
250 μL   Get quote  
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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

ALDH7A1 Antibody (YA2034) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ALDH7A1.
Background

ALDH7A1, a versatile enzyme, plays a crucial role in mediating essential protective effects within cells. It catalyzes the conversion of betaine aldehyde to betaine, serving as a vital cellular osmolyte and methyl donor. Notably, ALDH7A1 functions as a protective shield against oxidative stress by metabolizing various aldehydes derived from lipid peroxidation. Furthermore, the enzyme actively participates in lysine catabolism, contributing to broader metabolic processes. Through its multifaceted activities, ALDH7A1 emerges as a key player in cellular defense mechanisms and essential metabolic pathways.
Gene ID
SwissProt ID
Synonyms
aldehyde dehydrogenase 7 family member A1; EPD; PDE; ATQ1
Molecular Weight

Predicted band size: 58 kDa; Observed band size: 58 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Signal Transduction
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse
Dilution Ratio

WB: 1:500-1:1000; IF: 1:50-1:200; IP: 1:20

  • Western blot analysis was performed on extracts from HepG2 (lane 1, 15 μg), HT-29 (lane 2, 15 μg), Hela (lane 3, 15 μg), 293T (lane 4, 15 μg), SH-SY5Y (lane 5, 15 μg), and A549 (lane 6, 15 μg) using ALDH7A1 Rabbit mAb.Proteins were transferred to a PVDF membrane and blocked with 5% non - fat milk in TBST at 4°C overnight.The primary antibody (1:1000 dilution) and the loading control antibody (GAPDH, HY-P80137, 1:60000 dilution) were incubated in 5% non-fat milk in TBST for 1 hour at 37°C.Goat Anti - Rabbit IgG - HRP Secondary Antibody (1:20000 dilution) was then applied for 40 minutes at 37°C.
Application

WB, ICC/IF, IP
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthetic peptide of human ALDH7A1
Database

Entrez Gene: 501 Human ; 110695 Mouse ;

SwissProt: P49419 Human ; Q9DBF1 Mouse ;

OMIM: 266100 Human

Documentation
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

ALDH7A1 Antibody (YA2034) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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ALDH7A1 Antibody (YA2034)
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HY-P82289
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