AK3L1 Antibody (YA2693)

AK3L1 Antibody (YA2693) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2693), targeting AK3L1, with a predicted molecular weight of 25 kDa (observed band size: 25 kDa). AK3L1 Antibody (YA2693) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human background.

The AK3L1 protein is actively involved in maintaining cellular nucleotide homeostasis by catalyzing the interconversion of nucleoside phosphates. This versatile enzyme efficiently phosphorylates AMP and dAMP using ATP as a phosphate donor, and selectively phosphorylates AMP when utilizing GTP as the phosphate donor. Additionally, AK3L1 displays broad nucleoside diphosphate kinase activity, further contributing to its role in nucleotide metabolism. Beyond its nucleotide-related functions, AK3L1 plays a crucial role in controlling cellular ATP levels by regulating the phosphorylation and activation of the energy sensor protein kinase AMPK. Moreover, it serves a protective function in the cellular response to oxidative stress, highlighting its significance in cellular responses to various physiological conditions.

P27144

Predicted band size: 25 kDa; Observed band size: 25 kDa

Affinity Purified

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/20

WB, IHC-F, IHC-P, ICC/IF, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human AK3L1