1. Antibodies
  2. Primary Antibodies
  3. Monoclonal Antibodies
  4. alpha 1 Antitrypsin Antibody (YA4717)

alpha 1 Antitrypsin Antibody (YA4717)

Cat. No.: HY-P85025
User Guide for Antibodies Technical Support

alpha 1 Antitrypsin Antibody (YA4717) is a mouse-derived and non-conjugated monoclonal antibody, targeting to AAT. It can be applicated for WB, ELISA assays, in the background of human, mouse.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

alpha 1 Antitrypsin Antibody (YA4717) is a mouse-derived and non-conjugated monoclonal antibody, targeting to AAT. It can be applicated for WB, ELISA assays, in the background of human, mouse.

Background

SERPINA1 is an inhibitor of serine proteases, primarily targeting elastase with moderate affinity for plasmin and thrombin. It irreversibly inhibits trypsin, chymotrypsin, and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, reduces coagulation time, and exhibits proteolytic activity against insulin and plasmin. by similar: SERPINA1 also acts as a reversible chymotrypsin inhibitor, inhibiting elastase but not trypsin, with its major physiological role being the protection of the lower respiratory tract from proteolytic damage by human leukocyte elastase (HLE).

Gene ID
SwissProt ID
Synonyms
SERPINA1; AAT; PI; Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1
Molecular Weight

Predicted band size: 47 kDa;

Purity

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human, Mouse

Dilution Ratio

WB: 1:500-1:2000; ELISA: 1:10000

Application

WB, ELISA

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Immunogen

Purified recombinant fragment of human AAT expressed in E. Coli.

Documentation

alpha 1 Antitrypsin Antibody (YA4717) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
alpha 1 Antitrypsin Antibody (YA4717)
Cat. No.:
HY-P85025
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