14-3-3 epsilon Antibody (YA2629)

Cat. No.: HY-P82884: Data Sheet COA
SDS
User Guide for Antibodies
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14-3-3 epsilon Antibody (YA2629) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2629), targeting 14-3-3 epsilon, with a predicted molecular weight of 29 kDa (observed band size: 29 kDa). 14-3-3 epsilon Antibody (YA2629) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

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Description	14-3-3 epsilon Antibody (YA2629) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2629), targeting 14-3-3 epsilon, with a predicted molecular weight of 29 kDa (observed band size: 29 kDa). 14-3-3 epsilon Antibody (YA2629) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.
Background	The 14-3-3 epsilon protein serves as an adapter implicated in the regulation of a diverse array of both general and specialized signaling pathways, binding to numerous partners through the recognition of phosphoserine or phosphothreonine motifs, thereby modulating the activity of the binding partner. Notably, it positively regulates the nuclear export of phosphorylated protein HSF1 to the cytoplasm. Existing as a homodimer, it also forms heterodimers with YWHAZ and interacts with various proteins, including PKA-phosphorylated AANAT, ABL1 in its phosphorylated form, ARHGEF28, BEX3, CDKN1B, the 'Thr-369' phosphorylated form of DAPK2, DENND1A, GAB2, phosphorylated GRB10, KSR1, NDEL1, PI4KB, TBC1D22A, TBC1D22B, the phosphorylated form of SRPK2, TIAM2, the 'Ser-1134' and 'Ser-1161' phosphorylated form of SOS1, ZFP36, SLITRK1, HSF1 in its phosphorylated form, RIPOR2, KLHL22, CRTC1, CRTC2 (probably when phosphorylated at 'Ser-171'), CRTC3 (probably when phosphorylated at 'Ser-162' and/or 'Ser-273'), ATP2B1, ATP2B3, and MEFV. These interactions highlight the multifaceted role of 14-3-3 epsilon in orchestrating various cellular processes and signaling events.
Gene ID	7531 [NCBI]
SwissProt ID	P62258
Synonyms	14-3-3 epsilon; 14-3-3E; 143E; KCIP-1; MDCR; Protein kinase C inhibitor protein-1; YWHAE
Molecular Weight	Predicted band size: 29 kDa; Observed band size: 29 kDa
Purity	Affinity Chromatography
Conjugation	Non-conjugated
Modification	Unmodified
Research Field	Neuroscience
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Mouse, Rat
Dilution Ratio	WB: 1/500-1/1000; IHC: 1/50-1/100; IF: 1/50-1/200; FC: 1/50-1/100
Application	WB, IHC-P, ICC/IF, FC
Appearance	Liquid
Formulation	Supplied in rabbit IgG in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthesized peptide derived from human 14-3-3 epsilon
Database	Entrez Gene: 7531 Human ; 22627 Mouse ; 29753 Rat SwissProt: P62258 Human ; P62259 Mouse ; P62260 Rat OMIM: 605066 Human
Documentation	Select Batch: Data Sheet (236 KB) SDS (251 KB) COA (206 KB) User Guide for Antibodies (1077 KB)

14-3-3 epsilon Antibody (YA2629) Related Classifications

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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14-3-3 epsilon Antibody (YA2629)

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14-3-3 epsilon Antibody (YA2629) Related Classifications

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