1. Anti-infection NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  2. Bacterial Reactive Oxygen Species (ROS)
  3. Anti-MRSA agent 36

Anti-MRSA agent 36 (Compound III13) is an antibacterial agent with strong anti MRSA activity (MIC = 1 μg/mL). Anti-MRSA agent 36 targets phosphatidylglycerol (PG) on bacterial membranes, disrupting membrane integrity, leading to DNA leakage and increased ROS. Anti-MRSA agent 36 has advantages such as low cytotoxicity, low hemolysis, difficulty in inducing drug resistance, and good plasma stability. Anti-MRSA agent 36 can be used for the study of skin abscess and systemic infection models.

For research use only. We do not sell to patients.

Anti-MRSA agent 36

Anti-MRSA agent 36 Chemical Structure

CAS No. : 3096122-10-7

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Description

Anti-MRSA agent 36 (Compound III13) is an antibacterial agent with strong anti MRSA activity (MIC = 1 μg/mL). Anti-MRSA agent 36 targets phosphatidylglycerol (PG) on bacterial membranes, disrupting membrane integrity, leading to DNA leakage and increased ROS. Anti-MRSA agent 36 has advantages such as low cytotoxicity, low hemolysis, difficulty in inducing drug resistance, and good plasma stability. Anti-MRSA agent 36 can be used for the study of skin abscess and systemic infection models[1].

Molecular Weight

603.57

Formula

C29H35BrN2O5S

CAS No.
SMILES

CCCCCCNC(C[N+]1=CC=C(SCCCCCOC2=C(O3)C(C=CC3=O)=CC4=C2OC=C4)C=C1)=O.[Br-]

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Anti-MRSA agent 36
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HY-178476
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