2. Others GPCR/G Protein Neuronal Signaling Immunology/Inflammation Anti-infection
  3. Reference Standards Histamine Receptor HBV
  4. Antazoline hydrochloride (Standard)

Antazoline hydrochloride (Standard)  (Synonyms: Phenazoline hydrochloride (Standard))

Cat. No.: HY-B1067R Purity: ≥98%
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Antazoline (hydrochloride) (Standard) is the analytical standard of Antazoline (hydrochloride). This product is intended for research and analytical applications. Antazoline hydrochloride is a histamine H1 receptor antagonist with anticholinergic and antiviral properties. Antazoline hydrochloride can prevent histamine from acting on target cells through a reversible competition effect on histamine receptor sites of these cells. Antazoline hydrochloride can exert an antiallegic effect and prevent the occurrence of physiological reactions from the effect of blocking as well as inhibiting H1 receptor. Antazoline hydrochloride can effectively reduce HBV DNA in the extracellular supernatant in a dose-dependent manner, with EC50 of 2.910 μmol/L in HepAD38 cells. Antazoline hydrochloride also has a significant inhibitory effect on HBV DNA in the extracellular supernatant of Huh7 cells (EC50 = 2.349 μmol/L). Antazoline hydrochloride has anti-arrhythmic effect in acute myocardial infarctions. Antazoline hydrochloride can be studied in research for cardiovascular diseases, and HBV.

For research use only. We do not sell to patients.

Antazoline hydrochloride (Standard) Chemical Structure

Antazoline hydrochloride (Standard) Chemical Structure

CAS No. : 2508-72-7

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Description

Antazoline (hydrochloride) (Standard) is the analytical standard of Antazoline (hydrochloride). This product is intended for research and analytical applications. Antazoline hydrochloride is a histamine H1 receptor antagonist with anticholinergic and antiviral properties. Antazoline hydrochloride can prevent histamine from acting on target cells through a reversible competition effect on histamine receptor sites of these cells. Antazoline hydrochloride can exert an antiallegic effect and prevent the occurrence of physiological reactions from the effect of blocking as well as inhibiting H1 receptor. Antazoline hydrochloride can effectively reduce HBV DNA in the extracellular supernatant in a dose-dependent manner, with EC50 of 2.910 μmol/L in HepAD38 cells. Antazoline hydrochloride also has a significant inhibitory effect on HBV DNA in the extracellular supernatant of Huh7 cells (EC50 = 2.349 μmol/L). Antazoline hydrochloride has anti-arrhythmic effect in acute myocardial infarctions. Antazoline hydrochloride can be studied in research for cardiovascular diseases, and HBV.

Molecular Weight

301.81

Formula

C17H20ClN3
CAS No.
SMILES

[H]Cl.C1(CN(C2=CC=CC=C2)CC3=CC=CC=C3)=NCCN1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Antazoline hydrochloride (Standard) Related Classifications

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Keywords:

Antazoline hydrochloride (Standard)2508-72-7Phenazoline hydrochloride (Standard)Reference StandardsHistamine ReceptorHBVHepatitis B virusInhibitorinhibitorinhibit

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