Aminooxy-PEG3-C2-thiol hydrochloride

Cat. No.: HY-134512A: Data Sheet Handling Instructions
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Aminooxy-PEG3-C2-thiol (hydrochloride) is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

For research use only. We do not sell to patients.

Aminooxy-PEG3-C2-thiol hydrochloride Chemical Structure

Size	Stock	Quantity
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Aminooxy-PEG3-C2-thiol hydrochloride:

Aminooxy-PEG3-C2-thiol Get quote

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Biological Activity
Purity & Documentation
References
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Description

Aminooxy-PEG3-C2-thiol (hydrochloride) is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules^[1].

Molecular Weight

261.77

Formula

C₈H₂₀ClNO₄S

Appearance

Liquid

SMILES

NOCCOCCOCCOCCS.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : ≥ 125 mg/mL (477.52 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.8201 mL	19.1007 mL	38.2015 mL
5 mM	0.7640 mL	3.8201 mL	7.6403 mL
10 mM	0.3820 mL	1.9101 mL	3.8201 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.8201 mL	19.1007 mL	38.2015 mL	95.5037 mL
	5 mM	0.7640 mL	3.8201 mL	7.6403 mL	19.1007 mL
	10 mM	0.3820 mL	1.9101 mL	3.8201 mL	9.5504 mL
	15 mM	0.2547 mL	1.2734 mL	2.5468 mL	6.3669 mL
	20 mM	0.1910 mL	0.9550 mL	1.9101 mL	4.7752 mL
	25 mM	0.1528 mL	0.7640 mL	1.5281 mL	3.8201 mL
	30 mM	0.1273 mL	0.6367 mL	1.2734 mL	3.1835 mL
	40 mM	0.0955 mL	0.4775 mL	0.9550 mL	2.3876 mL
	50 mM	0.0764 mL	0.3820 mL	0.7640 mL	1.9101 mL
	60 mM	0.0637 mL	0.3183 mL	0.6367 mL	1.5917 mL
	80 mM	0.0478 mL	0.2388 mL	0.4775 mL	1.1938 mL
	100 mM	0.0382 mL	0.1910 mL	0.3820 mL	0.9550 mL