AH-D peptide TFA 

AH-D peptide TFA is an antiviral peptide that selectively disrupts membrane structures within the size range of exosomes, inducing T-EXO depletion and enhancing cancer immunotherapy^[1].

3283.75 (free base)

C₁₅₄H₂₂₈N₃₈O₄₀S.xC₂HF₃O₂

Solid

d-{Ser-Gly-Ser-Trp-Leu-Arg-Asp-Val-Trp-Asp-Trp-Ile-Cys-Thr-Val-Leu-Thr-Asp-Phe-Lys-Thr-Trp-Leu-Gln-Ser-Lys-Leu-NH2}

d-{SGSWLRDVWDWICTVLTDFKTWLQSKL-NH2}

OC(C(F)(F)F)=O.O=C([C@H](N)CO)NCC(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N)=O)CC(C)C)=O)CCCCN)=O)CO)=O)CCC(N)=O)=O)CC(C)C)=O)CC1=CNC2=CC=CC=C12)=O)[C@H](C)O)=O)CCCCN)=O)CC3=CC=CC=C3)=O)CC(O)=O)=O)[C@H](C)O)=O)CC(C)C)=O)C(C)C)=O)[C@H](C)O)=O)CS)=O)[C@@H](CC)C)=O)CC4=CNC5=CC=CC=C45)=O)CC(O)=O)=O)CC6=CNC7=CC=CC=C67)=O)C(C)C)=O)CC(O)=O)=O)CCCNC(N)=N)=O)CC(C)C)=O)CC8=CNC9=CC=CC=C89)=O)CO)=O.[x]

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Sol Shin, et al. Curvature-sensing peptide inhibits tumour-derived exosomes for enhanced cancer immunotherapy. Nat Mater. 2023 May;22(5):656-665.  [Content Brief]