2. Signaling Pathways
  3. SOS1
  4. SOS1 Agonist

SOS1 Agonist

SOS1 Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-153606
    SOS1 agonist-1
    		Agonist
    SOS1 agonist-1 (compound 79) is an agonist for the Son of sevenless homologue SOS1. SOS1 is a guanine nucleotide exchange factor that catalyzes the exchange of GDP to GTP on RAS and regulates RAS activation. SOS1 agonists increase nucleotide exchange on RAS, enhance cellular RAS-GTP levels, and trigger biphasic signaling changes in ERK1/2 phosphorylation. Play an anti-cancer role[1].