2. Signaling Pathways
  3. Immunology/Inflammation
  4. SOD
  5. SOD Inducer

SOD Inducer

SOD Inducers (2):

Cat. No. Product Name Effect Purity
  • HY-W026772
    Fluorene
    		Inducer 99.35%
    Fluorene is an orally active polycyclic aromatic hydrocarbon (PAH) and a precursor to other fluorene-based compounds. Fluorene and its derivatives serve as dye precursors for fluorene synthesis. In A549 cells, Fluorene induces oxidative stress and inflammatory responses by increasing ROS and SOD generation, exacerbating lipid peroxidation, modulating antioxidant enzyme activity, and upregulating the expression of pro-inflammatory factors TNF-α and IL-6. In vivo, Fluorene exhibits anxiolytic activity. Fluorene holds potential for research in inflammation and neurological disorders.
  • HY-175352
    Nurr1 Agonist 14
    		Inducer
    Nurr1 Agonist 14 (Compound 32) is a Nurr1 agonist with an EC50 of 0.09  μM for Nurr1. Nurr1 Agonist 14 has significant neuroprotective activity with no influence of residual DHODH inhibition. Nurr1 Agonist 14 upregulates neuroprotective genes including SOD2, SESN3, BIRC5, XIAP, FLRT2 and CRMP4 in dopaminergic neurons. Nurr1 Agonist 14 can be used for neurodegenerative diseases such as Alzheimer′s disease (AD), Parkinson′s disease (PD) and multiple sclerosis (MS) research.