2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. PI4P5K
  5. PI4P5K Inhibitor

PI4P5K Inhibitor

PI4P5K Inhibitors (5):

Cat. No. Product Name Effect Purity
  • HY-16937
    ISA-2011B
    		Inhibitor 99.85%
    ISA-2011B is a PIP5K1α inhibitor with promising anticancer effects .
  • HY-110150
    UNC3230
    		Inhibitor 99.39%
    UNC3230 is a potent, selective and ATP-competitive PIP5K1C inhibitor with an IC50 of ~41 nM. UNC3230 also inhibits PIP4K2C and does not inhibit any of the other lipid kinases that regulate phosphoinositide levels. UNC3230 has antinociceptive and anticancer effects.
  • HY-163476
    PIP5K1C-IN-1
    		Inhibitor 98.71%
    PIP5K1C-IN-1 (Compound 30) is a potent PIP5K1C inhibitor, with an IC50 of 0.80 nM. PIP5K1C-IN-1 exhibits low total clearance in mice and high levels of kinase selectivity. PIP5K1C-IN-1 can be used for the research of cancer and chronic pain.
  • HY-163572
    PIP5K1α-IN-1
    		Inhibitor 99.81%
    PIP5K1α-IN-1 (Compound 3e) is an inhibitor for phosphatidylinositol 4-phosphate 5-kinase type I α (PIP5K1α) with an IC50 of 0.46 μM.
  • HY-163477
    PIP5K1C-IN-2
    		Inhibitor
    PIP5K1C-IN-2 (compound 33) is a potent and selective 4-phosphate 5-kinases 1 C (PIP5K1C) inhibitor with an IC50 value of 0.0059 µM.