2. Signaling Pathways
  3. GPCR/G Protein
  4. Orphan GPCR
  5. Orphan GPCR Antagonist

Orphan GPCR Antagonist

Orphan GPCR Antagonist (1):

Cat. No. Product Name Effect Purity
  • HY-155417
    GPR34 receptor antagonist 3
    		Antagonist 99.88%
    GPR34 receptor antagonist 3 (Compound 5e) is a class of GRP34 antagonists, IC50 is 0.680 μM. GPR34 receptor antagonist 3 inhibited ERK1/2 phosphorylation induced by lysophosphatidylserine in a dose-dependent way without obvious cytotoxicity. GPR34 receptor antagonist 3 shows antisensory activity in mouse neuropathic pain model .