2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. NEKs
  5. NEK7 Isoform
  6. NEK7 Inhibitor

NEK7 Inhibitor

NEK7 Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-163358
    SLC3037
    		Inhibitor 99.85%
    SLC3037 is a NLRP3 inhibitor which blocks NLRP3 from binding to NEK7 or oligomerization, inhibiting inflammasome caused by MSU and other inflammasome activators. SLC3037 can be used for research of gout, cardiovascular diseases, metabolic syndrome or neurodegenerative diseases.
  • HY-174270
    NLRP3-IN-79
    		Inhibitor
    NLRP3-IN-79 (Compound B6) is a selective NLRP3 inflammasome inhibitor with an IC50 value of 10.69 nM. NLRP3-IN-79 blocks the assembly of the NLRP3 inflammasome by disrupting the NEK7-NLRP3 interaction. NLRP3-IN-79 is promising for research of NLRP3-driven inflammatory diseases such as systemic inflammation, peritonitis, and colitis.