2. Signaling Pathways
  3. GPCR/G Protein
  4. Natriuretic Peptide Receptor (NPR)

Natriuretic Peptide Receptor (NPR)

Natriuretic Peptide Receptor; NPR; NPR-A; NPR-B; NPR-C

Natriuretic peptide receptors can be divided into three types: NPR-A, NPR-B (guanylate cyclase-A and guanylate cyclase-B) and NPR-C. All three receptors have an effect on biological second messengers. NPR-A and NPR-B are guanylate cyclase receptors, and their activation can lead to increased cGMP levels, while the activation of NPR-C can lead to the inhibition of adenylate cyclase activity and increased phospholipase C activity. Natriuretic peptide receptors play an important role in the regulation of blood pressure and cardiovascular homeostasis[1].

Natriuretic Peptide Receptor (NPR) Related Products (25):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P1573
    Brain Natriuretic Peptide-45, rat
    Brain Natriuretic Peptide-45, rat (BNP-45, rat) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency.
    Brain Natriuretic Peptide-45, rat
  • HY-P3759
    BNP (22-46), Pro (Human)
    		Activator
    BNP (22-46), Pro (Human) is an peptide . BNP (22-46), Pro (Human) can be used for the research of cardiac dysfunction.
    BNP (22-46), Pro (Human)
  • HY-P3774
    [Tyr8]-Atrial Natriuretic Peptide (5-27), rat
    [Tyr8]-Atrial Natriuretic Peptide (5-27), rat is an atrial natriuretic peptide (ANP) analog that relaxes smooth muscle without affecting cGMP levels.
    [Tyr8]-Atrial Natriuretic Peptide (5-27), rat
  • HY-120147
    Ethiazide
    Ethiazide is a thiazole diuretic which inhibits renal reabsorption of sodium and water, thereby increasing urine excretion, reducing fluid retention, and lowering blood volume and blood pressure. Ethiazide can be used for cardiovascular research.
    Ethiazide
  • HY-P3772
    [Mpr7, DAla9] ANP (7-28), amide, rat
    [Mpr7, DAla9] ANP (7-28), amide, rat is an atrial peptide.
    [Mpr7, DAla9] ANP (7-28), amide, rat