2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. MetAP
  5. MetAP Degrader

MetAP Degrader

MetAP Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-161742
    Fumagilin-105
    		Degrader
    Fumagilin-105 is an autophagy-targeting chimera (AUTOTAC) that degrades MetAP2 via p62-mediated macroautophagy in a ubiquitination-independent manner. Fumagilin-105 can inhibit the migration of tumor cells and induce programmed cell death. Fumagilin-105 has anti-tumor activity. (p62-ZZ ligand (HY-W489121); target-binding ligand (HY-B0751); linker (HY-W245803)).