2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Liposome Related Products (839):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-40118
    Boc-Pro-OMe
    		99.80%
    Boc-Pro-OMe (Boc-L-proline methyl ester) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
    Boc-Pro-OMe
  • HY-141617
    1-Palmitoyl-2-hydroxy-sn-glycero-3-PE
    		99.10%
    1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring choline phospholipid that can be synthesized from phosphatidylcholine and fatty acids. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is used as a structure-related lipid control.
    1-Palmitoyl-2-hydroxy-sn-glycero-3-PE
  • HY-157423
    16:1 (DELTA 9-Cis) PC
    		99.0%
    16:1 (DELTA 9-Cis) PC is a phospholipid metabolite .
    16:1 (DELTA 9-Cis) PC
  • HY-140741
    DSPE-PEG-OH, MW 2000
    		99.89%
    DSPE-PEG-OH, MW 2000 is a hydroxyl-terminated PEGylated phospholipid. The hydrophobic tail allows for the encapsulation and aggregation of other hydrophobic drugs, and the hydroxyl terminus is suitable for further reactions. DSPE-PEG-OH, MW 2000 can be used to prepare liposomes or lipid nanoparticles.
    DSPE-PEG-OH, MW 2000
  • HY-160439
    Ionizable lipid-2
    		99.77%
    Ionizable lipid-2 (Compound 1) is an ionizable lipid that can be used for the preparation of lipid nanoparticles and vaccine research.
    Ionizable lipid-2
  • HY-157624
    1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine
    		99.0%
    1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (18:0-22:6 PE) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
    1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine
  • HY-153737
    113-N16B
    		98.0%
    113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
    113-N16B
  • HY-W714524
    1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine sodium
    		99.13%
    2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes.
    1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine sodium
  • HY-P2982
    Ceramide 1-phosphate
    Ceramide 1-phosphate is a bioactive lipid and one of the key components of sphingolipids. Ceramide 1-phosphate playing diverse roles in cellular behaviors such as cell differentiation, migration, proliferation and death.
    Ceramide 1-phosphate
  • HY-142654
    ATX-002
    		98.0%
    ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively.
    ATX-002
  • HY-142986
    Dlin-MeOH
    		98.0%
    Dlin-MeOH is a lipid product for use in drug delivery systems.
    Dlin-MeOH
  • HY-144014
    MVL5
    		98.34%
    MVL5 is a non-degradable multivalent cationic lipid. MVL5 is a highly efficient vector for both DNA and siRNA. MVL5 can be used in breast cancer research.
    MVL5
  • HY-172494
    DSPE-PEG2000-iRGD
    DSPE-PEG2000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG2000-iRGD can be used for drug delivery.
    DSPE-PEG2000-iRGD
  • HY-154804
    DLin-M-C4-DMA
    		98.0%
    DLin-M-C4-DMA (Compound MC4) is a cationic lipid. DLin-M-C4-DMA can be used for delivery of nucleic acids.
    DLin-M-C4-DMA
  • HY-159700
    AA3-DLin
    		99.0%
    AA3-DLin is an ionizable cationic lipid with a pKa value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model.
    AA3-DLin
  • HY-170706
    DSPE-PEG2000-COOH
    		99.95%
    DSPE-PEG(2000)-COOH is a PEGylated derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (HY-112530).
    DSPE-PEG2000-COOH
  • HY-144768
    (R)-Chol-TPP
    (R)-Chol-TPP a mitochondria targeting liposome ligand could be used in pH-redox responsive.
    (R)-Chol-TPP
  • HY-142977
    6-Oxohexyl 2-hexyldecanoate, 80% (ELSD)
    6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an intermediate in the synthesis of ALC-0315. ALC-0315 is an ionizable amino lipid. ALC-0315 is a key component of LNP delivery vehicles. 6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an effective delivery vehicle of mRNA.
    6-Oxohexyl 2-hexyldecanoate, 80% (ELSD)
  • HY-153852
    LNP Lipid-7
    LNP Lipid-7 is a cationic lipid. LNP Lipid-7 can be used to prepare lipid nanoparticles (LNPs) for the delivery of drugs such as nucleic acids.
    LNP Lipid-7
  • HY-W441004
    DSPE-Thiol
    DSPE-Thiol is a phophalipid capped with thiol group. The thiol capped head can selectively react with maleimide. DSPE-Thiol can also be used for the preparation of phospholipid dimers.
    DSPE-Thiol