2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Liposome Related Products (870):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-143702
    Fluorescent DOTAP
    Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research.
    Fluorescent DOTAP
  • HY-170333
    Lipid A-11
    		99.84%
    Lipid A-11 (CICL1) can be used to synthesize lipid-like nanoparticles (LNPs) for delivery of nucleic acids.
    Lipid A-11
  • HY-145742
    1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium
    		98.0%
    1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is the component of liposomes for drug delivery.
    1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium
  • HY-156857
    PPZ-A10
    		Chemical 98.0%
    PPZ-A10 is an ionizable cationic lipid. PPZ-A10 preferentially delivers mRNA to liver and spleen immune cells. Pi-LNPs containing PPZ-A10 can effectively deliver mRNA/siRNA to solid tumors.
    PPZ-A10
  • HY-112768
    PEG2000-DMPE
    		Chemical 99.70%
    PEG2000-DMPE can be used to synthsis a LNP. PEG2000-DMPE enhances the entrapment efficiency depending on the increasing portion in the liposome. The optimal formulation for animal study is that DMPC/PEG2000-DMPE/CH=50/5/45 at the weight ratio of drug/lipid=1/20.
    PEG2000-DMPE
  • HY-112772A
    98N12-5
    		98.0%
    98N12-5 is a novel multi-tail ionizable lipids that has been used for efficient in vivo siRNA-delivery to the liver.
    98N12-5
  • HY-B1555
    Benzyl nicotinate
    		99.60%
    Benzyl nicotinate is a vasodilator that increases skin oxygenation levels by increasing skin blood flow.
    Benzyl nicotinate
  • HY-143202
    DPhPC
    		99.77%
    DPhPC is a derivative of phosphatidylcholine (PC) used to synthesize bilayer vesicle phospholipids. DPhPC bilayer membranes do not leak ions in the absence of pores or ion channels, so they are often used to study the activity of ion channels and the regulation of membrane potential. Nanoliposomes (NTG) prepared based on DPhPC can improve the bioavailability of nitric oxide (NO) and have anti-inflammatory effects.
    DPhPC
  • HY-22274
    DMPG sodium
    		99.16%
    DMPG sodium is a biochemical reagent. DMPG sodium is used as a liposome carrier to load 6-shogaol (HY-14616) with anticancer activity.
    DMPG sodium
  • HY-153378
    Lipid 15
    		98.0%
    Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
    Lipid 15
  • HY-151705
    Alkyne Cholesterol
    Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an alkyne group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization.
    Alkyne Cholesterol
  • HY-W130610
    Stearamide
    Stearamide is a primary fatty acid amide. Stearamide displays cytotoxic and ichthytoxic activity.
    Stearamide
  • HY-145795
    OF-02
    		≥98.0%
    OF-02 is an ionizable lipid for mRNA delivery and a key component of lipid nanoparticles (LNPs). OF-02 is protonated in the acidic endosomal environment to promote endosomal escape of mRNA and efficiently induce protein expression in target cells. OF-02 relies on the pH-responsive membrane fusion properties to form a complex with mRNA and destroy the endosomal membrane structure to achieve mRNA release in the cytoplasm. OF-02 is mainly used in the development of mRNA vaccines, gene editing, and protein replacement therapy[1][2][3].
    OF-02
  • HY-145793
    FTT5
    		98.0%
    FTT5 is an ionizable lipid that can be used to prepare lipid nanoparticles for efficient delivery of long-chain mRNA in vivo.
    FTT5
  • HY-115415
    1,2-Distearoyl-sn-glycero-3-phosphate sodium
    		98.0%
    1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt has unique chemical properties that make it an effective tool for encapsulating drugs and delivering them to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
    1,2-Distearoyl-sn-glycero-3-phosphate sodium
  • HY-133971
    Cholesterol 5α,6α-epoxide
    		98.40%
    Cholesterol-5α,6α-epoxide is an epoxide derivative of cholesterol formed by the enzymatic oxidation of cholesterol in the liver and other tissues. Cholesterol-5α,6α-epoxide has unique chemical properties that make it an important intermediate in the biosynthesis of bile acids, which play a key role in the digestion and absorption of dietary fats. It also has a potential physiological role in regulating cholesterol metabolism and transport, although its biological function is not fully understood.
    Cholesterol 5α,6α-epoxide
  • HY-148648
    Lipid 29
    		99.95%
    Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles.
    Lipid 29
  • HY-153879
    C12-TLRa
    		99.0%
    C12-TLRa is an ionized adjuvant lipid. C12-TLRa targets TLR7/8 receptors in endosomes. C12-TLRa enhances mRNA delivery as a structural component of LNPs. C12-TLRa enhances innate immune responses. C12-TLRa can be used for the research of SARS-CoV-2 mRNA vaccine.
    C12-TLRa
  • HY-W440719
    Cholesterol-PEG-MAL (MW 2000)
    Cholesterol-PEG-MAL (MW 2000) is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
    Cholesterol-PEG-MAL (MW 2000)
  • HY-143203
    18:0-18:2 PE
    		98.0%
    18:0-18:2 PE is an important component of phosphatidylethanolamine (PE), involved in phospholipid metabolism and associated with diseases such as ovarian cancer. 18:0-18:2 PE in the hot processing process, its unsaturated fatty acids will degrade to form a variety of odor active compounds. 18:0-18:2 PE is mainly used in the field of food science to improve the flavor of aquatic products, as well as medical research on diseases related to phospholipid metabolism.
    18:0-18:2 PE