2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Liposome Related Products (839):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-145793
    FTT5
    		≥98.0%
    FTT5 is an ionizable lipid that can be used to prepare lipid nanoparticles for efficient delivery of long-chain mRNA in vivo.
    FTT5
  • HY-B1555
    Benzyl nicotinate
    		99.60%
    Benzyl nicotinate is a vasodilator that increases skin oxygenation levels by increasing skin blood flow.
    Benzyl nicotinate
  • HY-42990
    Hydrogenated soya phosphatidylcholine
    		99.0%
    Hydrogenated soya phosphatidylcholine (hydrogenated soybean phosphatidylcholine) is a natural product. Hydrogenated soya phosphatidylcholine can extend drug release in regard to drug loading and solubility for oral drug delivery of watersoluble drugs.
    Hydrogenated soya phosphatidylcholine
  • HY-143702
    Fluorescent DOTAP
    Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research.
    Fluorescent DOTAP
  • HY-148855
    OF-C4-Deg-Lin
    		≥98.0%
    OF-C4-Deg-Lin is an ionizable lipid with varied linker lengths. OF-C4-Deg-Lin can be used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA.
    OF-C4-Deg-Lin
  • HY-112768
    PEG2000-DMPE
    		Chemical 99.70%
    PEG2000-DMPE can be used to synthsis a LNP. PEG2000-DMPE enhances the entrapment efficiency depending on the increasing portion in the liposome. The optimal formulation for animal study is that DMPC/PEG2000-DMPE/CH=50/5/45 at the weight ratio of drug/lipid=1/20.
    PEG2000-DMPE
  • HY-112772A
    98N12-5
    		98.0%
    98N12-5 is a novel multi-tail ionizable lipids that has been used for efficient in vivo siRNA-delivery to the liver.
    98N12-5
  • HY-148648
    Lipid 29
    		99.87%
    Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles.
    Lipid 29
  • HY-145742
    1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium
    		98.0%
    1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is the component of liposomes for drug delivery.
    1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium
  • HY-150118
    Lipid 8
    		≥98.0%
    Lipid 8 is an ionizable amino lipid that can be used to synthesize lipid nanoparticles (LNPs). Lipid 8 is applicable to research in drug delivery.
    Lipid 8
  • HY-W130610
    Stearamide
    Stearamide is a primary fatty acid amide. Stearamide displays cytotoxic and ichthytoxic activity.
    Stearamide
  • HY-145795
    OF-02
    		≥98.0%
    OF-02 is an ionizable lipid for mRNA delivery and a key component of lipid nanoparticles (LNPs). OF-02 is protonated in the acidic endosomal environment to promote endosomal escape of mRNA and efficiently induce protein expression in target cells. OF-02 relies on the pH-responsive membrane fusion properties to form a complex with mRNA and destroy the endosomal membrane structure to achieve mRNA release in the cytoplasm. OF-02 is mainly used in the development of mRNA vaccines, gene editing, and protein replacement therapy[1][2][3].
    OF-02
  • HY-153879
    C12-TLRa
    		99.0%
    C12-TLRa is an ionized adjuvant lipid. C12-TLRa targets TLR7/8 receptors in endosomes. C12-TLRa enhances mRNA delivery as a structural component of LNPs. C12-TLRa enhances innate immune responses. C12-TLRa can be used for the research of SARS-CoV-2 mRNA vaccine.
    C12-TLRa
  • HY-22274
    DMPG sodium
    		99.16%
    DMPG sodium is a biochemical reagent. DMPG sodium is used as a liposome carrier to load 6-shogaol (HY-14616) with anticancer activity.
    DMPG sodium
  • HY-137499
    NT1-O12B
    NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination.
    NT1-O12B
  • HY-151705
    Alkyne Cholesterol
    Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an alkyne group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization.
    Alkyne Cholesterol
  • HY-115415
    1,2-Distearoyl-sn-glycero-3-phosphate sodium
    		98.0%
    1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt has unique chemical properties that make it an effective tool for encapsulating drugs and delivering them to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
    1,2-Distearoyl-sn-glycero-3-phosphate sodium
  • HY-137501
    306-O12B-3
    		99.87%
    306-O12B-3 is a lipidoid that can efficiently deliver ASO both in vitro and in vivo. 306-O12B-3 is used to transport small molecule drugs across the blood-brain barrier (BBB).
    306-O12B-3
  • HY-143203
    18:0-18:2 PE
    		98.0%
    18:0-18:2 PE is an important component of phosphatidylethanolamine (PE), involved in phospholipid metabolism and associated with diseases such as ovarian cancer. 18:0-18:2 PE in the hot processing process, its unsaturated fatty acids will degrade to form a variety of odor active compounds. 18:0-18:2 PE is mainly used in the field of food science to improve the flavor of aquatic products, as well as medical research on diseases related to phospholipid metabolism.
    18:0-18:2 PE
  • HY-150115
    Lipid 10
    Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
    Lipid 10