2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Lipase
  5. Lipase Degrader

Lipase Degrader

Lipase Degraders (2):

Cat. No. Product Name Effect Purity
  • HY-163959
    PF-07853578
    		Degrader
    PF-07853578 (Example 11) is a PNPLA3 degrader with an EC50 of 8 nM. PNPLA3 degrader-1 can be used in the study of cirrhosis and hepatocellular carcinoma.
  • HY-173599
    NUV-244
    		Degrader
    NUV-244 is a PNPLA3 I148M degrader. NUV-244 reduces PNPLA3 I148M levels on lipid droplets via BFAR-mediated ubiquitin-proteasome degradation.