2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9804):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-114464S
    11-Beta-hydroxyandrostenedione-d4
    11-Beta-hydroxyandrostenedione-d4 is the deuterium labeled 11-Beta-hydroxyandrostenedione. 11-Beta-hydroxyandrostenedione (4-Androsten-11β-ol-3,17-dione) is a steroid mainly found in the the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue). 11-Beta-hydroxyandrostenedione is a 11β-hydroxysteroid dehydrogenase (11βHSD) isozymes inhibitor.
    11-Beta-hydroxyandrostenedione-d<sub>4</sub>
  • HY-W015882S1
    4-Methylpentanoic acid-d11
    		99.28%
    4-Methylpentanoic acid-d11 is the deuterium labeled 4-Methylpentanoic acid. 4-Methylpentanoic acid (Isocaproic Acid) is a Short chain fatty acid (SCFA).
    4-Methylpentanoic acid-d<sub>11</sub>
  • HY-130569S
    7-Hydroxymethotrexate-d3 sodium
    7-Hydroxymethotrexate-d3 (sodium) is deuterium labeled 7-Hydroxymethotrexate. 7-Hydroxymethotrexate is a major metabolite of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis.
    7-Hydroxymethotrexate-d<sub>3</sub> sodium
  • HY-W654020
    Propyl paraben-13C6
    		99.99%
    Propyl paraben-13C6 (Propyl parahydroxybenzoate-13C6) is 13C labeled Propylparaben. Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats.
    Propyl paraben-<sup>13</sup>C<sub>6</sub>
  • HY-17506S1
    Azithromycin-13C,d3
    		99.90%
    Azithromycin-13C,d3 is the deuterium and 13C labeled Azithromycin.
    Azithromycin-<sup>13</sup>C,d<sub>3</sub>
  • HY-141626S
    6β-Hydroxytestosterone-d7
    6β-Hydroxytestosterone-d7 is a deuterated labeled 6β-Hydroxytestosterone. 6β-Hydroxytestosterone is a major metabolite of Testosterone.
    6β-Hydroxytestosterone-d<sub>7</sub>
  • HY-70037AS
    Cinacalcet-d3 hydrochloride
    Cinacalcet-d3 (hydrochloride) is the deuterium labeled Cinacalcet (hydrochloride). Cinacalcet hydrochloride (AMG-073 hydrochloride) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.
    Cinacalcet-d<sub>3</sub> hydrochloride
  • HY-159191S
    VQPGQN(Phe-13C9,15N)HMFTKEKLEEVIKDI TFA
    VQPGQN(Phe-13C9,15N)HMFTKEKLEEVIKDI (TFA) is the 13C and 15N labeled isotope of VQPGQN-HMFTKEKLEEVIKDI (TFA).
    VQPGQN(Phe-<sup>13</sup>C<sub>9</sub>,<sup>15</sup>N)HMFTKEKLEEVIKDI TFA
  • HY-W094847S
    N-Eicosane-d42
    		99.00%
    N-Eicosane-d42 is the deuterium labeled N-Eicosane.
    N-Eicosane-d<sub>42</sub>
  • HY-B1619S
    Cromolyn-d5
    Cromolyn-d5 (Cromoglycate-d5) is the deuterium labeled Cromolyn (HY-B1619). Cromolyn (Cromoglycate) is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn can be used in the research of bronchial asthma. In addition, Cromolyn has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects.
    Cromolyn-d<sub>5</sub>
  • HY-W040193S4
    DSPC-d4
    		≥99.0%
    DSPC-d4 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d4) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
    DSPC-d<sub>4</sub>
  • HY-B0075S2
    Melatonin-d7
    		≥98.0%
    Melatonin-d7 is the deuterium labeled Melatonin (HY-B0075). Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress.
    Melatonin-d<sub>7</sub>
  • HY-18085S2
    Quercetin-13C3
    Quercetin-13C3 is the 13C-labeled Quercetin. Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively.
    Quercetin-<sup>13</sup>C<sub>3</sub>
  • HY-142283
    Dosimertinib-d3
    Dosimertinib-d3-d3 is a potent and orally active EGFR inhibitor. Dosimertinib-d3-d3 decreases the expression of p-EGFR and p-ERK protein levels. Dosimertinib-d3-d3 shows antiproliferative and anti-tumor activity. Dosimertinib-d3-d3 has the potential for the research of non-small-cell lung cancer (NSCLC).
    Dosimertinib-d<sub>3</sub>
  • HY-N11605S
    C16(plasm)-18:1(-d9) PC
    C16(plasm)-18:1(d9) PC (1-(1Z-hexadecenyl)-2-oleoyl(d9)-sn-glycero-3-phosphocholine) is deuterium labeled PC 16:0/18:1.
    C16(plasm)-18:1(-d<sub>9</sub>) PC
  • HY-B1449S5
    Uridine-d2
    		≥99.0%
    Uridine-d2 is the deuterium labeled Uridine.
    Uridine-d<sub>2</sub>
  • HY-10984S2
    Pomalidomide-d4
    Pomalidomide-d4 is the deuterium labeled Pomalidomide. Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors<
    Pomalidomide-d<sub>4</sub>
  • HY-W654013
    Minocycline-d7
    Minocycline-d7 is deuterium labeled Minocycline. Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect.
    Minocycline-d<sub>7</sub>
  • HY-10195BS
    Ruboxistaurin-d6 hydrochloride
    Ruboxistaurin-d6 (hydrochloride) is the deuterium labeled Ruboxistaurin hydrochloride. Ruboxistaurin (LY333531) hydrochloride is an orally active, selective PKC beta inhibitor (Ki=2 nM). Ruboxistaurin hydrochloride exhibits ATP dependent competitive inhibition of PKC beta I with an IC50 of 4.7 nM. Ruboxistaurin hydrochloride inhibits PKC beta II with an IC50 of 5.9 nM.
    Ruboxistaurin-d<sub>6</sub> hydrochloride
  • HY-B0361S1
    Aspartame-d5
    Aspartame-d5 is the deuterium labeled Aspartame. Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener. Aspartame is composed of phenylalanine (50%), aspartic acid (40%) and methanol (10%).
    Aspartame-d<sub>5</sub>