2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9804):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-131422S
    (Rac)-8-Hydroxy-efavirenz-d4
    rac 8-Hydroxy Efavirenz-d4 is the deuterium labeled rac 8-Hydroxy Efavirenz. rac 8-Hydroxy Efavirenz-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    (Rac)-8-Hydroxy-efavirenz-d<sub>4</sub>
  • HY-B0165CS
    Pravastatin-d3 sodium
    		99.02%
    Pravastatin-d3 (sodium) is the deuterium labeled Pravastatin sodium salt. Pravastatin (CS-514) sodium salt is a competitive HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.
    Pravastatin-d<sub>3</sub> sodium
  • HY-10250S1
    Triciribine phosphate-d3
    Triciribine phosphate-d3 (TCN-P-d3) is a deuterated compound of Triciribine phosphate (TCN-P). TCN-P inhibits adenosine monophosphate (AMP)-activated protein kinase through an allosteric mechanism, affecting the first key step in de novo purine biosynthesis. Triciribine phosphate also inhibits inosine monophosphate dehydrogenase, which is the first key step in guanosine nucleotide synthesis. Triciribine phosphate does not affect ligase activity .
    Triciribine phosphate-d<sub>3</sub>
  • HY-113294S
    3-Hydroxykynurenine-13C3,15N
    		98.74%
    3-Hydroxykynurenine-13C3,15N (3-Hydroxy-DL-kynurenine-13C3,15N) is the 13C and 15N labeled 3-Hydroxykynurenine (HY-113294). 3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis.
    3-Hydroxykynurenine-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N
  • HY-13626S
    Spisulosine-d3
    		≥99.0%
    Spisulosine-d3 (ES-285-d3) is deuterium labeled Spisulosine (HY-13626). Spisulosine is an antiproliferative (antitumoral) compound of marine origin. Spisulosine inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKCζ activation. Spisulosine induces apoptosis in PC-3 and LNCaP cells.
    Spisulosine-d<sub>3</sub>
  • HY-B1832S
    Prednisone acetate-d3
    Prednisone acetate-d3 is the deuterium labeled Prednisone acetate. Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties.
    Prednisone acetate-d<sub>3</sub>
  • HY-W578976S
    N-Boc-piperazine-d4
    N-Boc-piperazine-d4 is the deuterium labeled N-Boc-piperazine.
    N-Boc-piperazine-d<sub>4</sub>
  • HY-B0149S1
    Tranexamic acid-d2-1
    		99.19%
    Tranexamic acid-d2-1 is the deuterium labeled Tranexamic acid. Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.
    Tranexamic acid-d<sub>2</sub>-1
  • HY-W770434
    Octrizole-13C6
    Octrizole-13C6 is 13C labeled Octrizole.
    Octrizole-<sup>13</sup>C<sub>6</sub>
  • HY-100057S
    BMY 28674-d8
    BMY 28674-d8 is the deuterium labeled BMY 28674.
    BMY 28674-d<sub>8</sub>
  • HY-W010255AS
    Phenylglyoxylic acid-d5 sodium
    		99.79%
    Phenylglyoxylic acid-d5 (sodium) is the deuterium labeled Phenylglyoxylic acid (sodium).
    Phenylglyoxylic acid-d<sub>5</sub> sodium
  • HY-123689S1
    Samidorphan-d5
    Samidorphan-d5 (ALKS-33-d5) is is a deuterated compound of Samidorphan. Samidorphan is an orally active opioid system modulator that binds with high affinity to μ-opioid, κ-opioid, and δ-opioid receptors. Samidorphan is a μ-opioid receptor antagonist and a partial agonist at k-opioid and δ-opioid receptors. Samidorphan acts primarily as an opioid receptor antagonist in vivo.
    Samidorphan-d<sub>5</sub>
  • HY-15453S
    Devimistat-d10
    		99.79%
    Devimistat-d10 (CPI-613-d10) is the deuterium-labeled Devimistat (HY-15453).
    Devimistat-d<sub>10</sub>
  • HY-W127840
    Ethylene-d4-diamine
    Ethylene-d4-diamine is the deuterium labeled Ethylene-diamine.
    Ethylene-d<sub>4</sub>-diamine
  • HY-B0519AS
    Tylosin-d3
    Tylosin-d3 is the deuterium labeled Tylosin. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle.
    Tylosin-d<sub>3</sub>
  • HY-123007S
    13(S)-HODE-d4
    		99.2%
    13(S)-HODE-d4 is the deuterium labeled 13(S)-HODE.
    13(S)-HODE-d<sub>4</sub>
  • HY-B1378S
    Ethosuximide-d3
    		≥99.0%
    Ethosuximide-d3 is the deuterium labeled Ethosuximide. Ethosuximide, a widely prescribed anti-epileptic agent, improves the phenotypes of multiple neurodegenerative disease models and blocks the low voltage activated T-type calcium channel.
    Ethosuximide-d<sub>3</sub>
  • HY-B0098BS
    Doxazosin-d8 hydrochloride
    		99.53%
    Doxazosin-d8 (hydrochloride) is the deuterium labeled Doxazosin hydrochloride.
    Doxazosin-d<sub>8</sub> hydrochloride
  • HY-176034S
    GPAGPQGP-Arg(13C6,15N4) TFA
    		99.58%
    GPAGPQGP-Arg (13C6,15N4) TFA is a peptide containing 13C6 and 15N4 labeled Arg.
    GPAGPQGP-Arg(<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>4</sub>) TFA
  • HY-N7032S1
    Uridine 5′-diphosphoglucose-13C6 disodium
    		98.35%
    Uridine 5′-diphosphoglucose-13C6 (UDP-D-Glucose-13C6) disodium is the 13C labeled Uridine 5′-diphosphoglucose disodium (HY-N7032). Uridine 5’-diphosphoglucose (UDP-glucose) disodium, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue.
    Uridine 5′-diphosphoglucose-<sup>13</sup>C<sub>6</sub> disodium