2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7656):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1473S
    Serotonin-d4 hydrochloride
    		98.58%
    Serotonin-d4 (5-Hydroxytryptamine-d4) hydrochloride is the deuterium labeled Serotonin (hydrochloride) (HY-B1473). Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
    Serotonin-d<sub>4</sub> hydrochloride
  • HY-B0451AS4
    Dopamine-d3 hydrochloride
    		99.30%
    Dopamine-d3 (hydrochloride) is the deuterium labeled Dopamine hydrochloride (ASL279)-[1].
    Dopamine-d<sub>3</sub> hydrochloride
  • HY-W001158S
    N,N-Dimethylglycine-d6 hydrochloride
    		99.46%
    N,N-Dimethylglycine-d6 (Dimethylglycine-d6) hydrochloride is the deuterium labeled N,N-Dimethylglycine hydrochloride (HY-W001158). N,N-Dimethylglycine (Dimethylglycine) hydrochloride, a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine hydrochloride is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine hydrochloride has antidepressant-like and surfactant effects.
    N,N-Dimethylglycine-d<sub>6</sub> hydrochloride
  • HY-132382S
    β-Sitosterol-d7 (Mixture of Diastereomers)
    		≥98.0%
    β-Sitosterol-d7 (Mixture of Diastereomers) is the deuterium labeled β-Sitosterol (mixture of diasteromers)[1].
    β-Sitosterol-d<sub>7</sub> (Mixture of Diastereomers)
  • HY-B0421S
    Mycophenolic acid-d3
    		99.59%
    Mycophenolic acid-d3 is deuterium labeled Mycophenolic acid, which is an an immunosuppresant agent and has potent anti-proliferative activity.
    Mycophenolic acid-d<sub>3</sub>
  • HY-N7148S
    α-Vitamin E-d6
    		≥99.0%
    α-Vitamin E-d6 is the deuterium labeled α-Vitamin E[1].
    α-Vitamin E-d<sub>6</sub>
  • HY-16562S1
    Irinotecan-d10 hydrochloride
    		99.76%
    Irinotecan-d10 (hydrochloride) is the deuterium labeled Irinotecan. Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex[1][2].
    Irinotecan-d<sub>10</sub> hydrochloride
  • HY-100805S
    D-Glutamic acid-d5
    		99.91%
    D-Glutamic acid-d5 is the deuterium labeled D-Glutamic acid. D-glutamic acid, an enantiomer of L- glutamic acid, is widely used in pharmaceuticals and foods[1].
    D-Glutamic acid-d<sub>5</sub>
  • HY-70002S1
    Enzalutamide-d6
    		99.84%
    Enzalutamide-d6 (MDV3100-d6) is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.
    Enzalutamide-d<sub>6</sub>
  • HY-133689AS
    3-Nitrophenylhydrazine-13C6 hydrochloride
    		98.26%
    3-Nitrophenylhydrazine-13C6 (hydrochloride) is the 13C labeled 3-Nitrophenylhydrazine hydrochloride[1].
    3-Nitrophenylhydrazine-<sup>13</sup>C<sub>6</sub> hydrochloride
  • HY-B0511S
    Biotin-d2-1
    		99.65%
    Biotin-d2-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
    Biotin-d<sub>2</sub>-1
  • HY-N0390S6
    L-Glutamine-13C5,15N2
    		≥98.0%
    L-Glutamine-13C5,15N2 is the 13C- and 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.
    L-Glutamine-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-132429S
    3-Indoxyl Sulfate-d5 potassium
    		99.77%
    3-Indoxyl Sulfate-d5 (potassium) is the deuterium labeled 3-Indoxyl Sulfate potassium[1].
    3-Indoxyl Sulfate-d<sub>5</sub> potassium
  • HY-18569S2
    3-Indoleacetic acid-2,2-d2
    		98.06%
    3-Indoleacetic acid-2,2-d2 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
    3-Indoleacetic acid-2,2-d<sub>2</sub>
  • HY-144243S
    Vitamin B5-d4 calcium
    		99.51%
    Vitamin B5-d4 (calcium) is the deuterium labeled Vitamin B5 calcium[1].
    Vitamin B5-d<sub>4</sub> calcium
  • HY-W017086S
    Dibenzo[b,d]furan-d8
    		99.90%
    Dibenzo[b,d]furan-d8 is the deuterium labeled Dibenzo[b,d]furan[1].
    Dibenzo[b,d]furan-d<sub>8</sub>
  • HY-41700S
    D-Alanine-d3
    		99.31%
    D-Alanine-d3 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
    D-Alanine-d<sub>3</sub>
  • HY-16561S
    Resveratrol-d4
    		99.36%
    Resveratrol-d4 is the deuterium labeled Resveratrol. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator. Resveratrol is a potent pregnane X receptor (PXR) inhibitor. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model. Resveratrol increases production of NO in endothelial cells.
    Resveratrol-d<sub>4</sub>
  • HY-N0667S2
    L-Asparagine-15N2 monohydrate
    		≥98.0%
    L-Asparagine-15N2 monohydrate is the 15N-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
    L-Asparagine-<sup>15</sup>N<sub>2</sub> monohydrate
  • HY-W010098S1
    Terephthalic acid-13C2
    		99.60%
    Terephthalic acid-13C2 is the 13C-labeled Terephthalic acid. Terephthalic acid is one isomer of the three phthalic, a precursor to the polyester PET, used to make clothing and plastic bottles.
    Terephthalic acid-<sup>13</sup>C<sub>2</sub>