2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9791):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-10208S
    Pazopanib-d6
    		≥98.0%
    Pazopanib-d6 is the deuterium labeled Pazopanib. Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.
    Pazopanib-d<sub>6</sub>
  • HY-12678S
    Entrectinib-d4
    Entrectinib-d4 (NMS-E628-d4; RXDX-101-d4) is the deuterium labeled Entrectinib (HY-12678). Entrectinib is an orally active, BBB-penetrated and centrally active inhibitor of TrkA/B/C, ROS1 and ALK, with IC50 values of 1, 3, 5, 12 and 7 nM, respectively. Entrectinib induces apoptosis and cycle arrest in cancer cells, has antitumor activity, and attenuates bleomycin-induced lung fibrosis in mice.
    Entrectinib-d<sub>4</sub>
  • HY-B0373S1
    Tiopronin-d3
    		99.42%
    Tiopronin-d3 is the deuterium labeled Tiopronin. Tiopronin is a diffusible antioxidant, an antidote to heavy metal poisoning and a radioprotective agent. Tiopronin can control the rate of cystine precipitation and excretion and has the potential for cystinuria, rheumatoid arthritis and hepatic disorders.
    Tiopronin-d<sub>3</sub>
  • HY-10917S
    GW2580-d6
    		98.36%
    GW2580-d6 is the deuterium labeled GW2580. GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 μM. GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling.
    GW2580-d<sub>6</sub>
  • HY-17413S2
    Zidovudine-d4
    Zidovudine-d4 is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.
    Zidovudine-d<sub>4</sub>
  • HY-127035S3
    Tristearin-d5
    		98.93%
    Tristearin-d5 is the deuterium labeled Tristearin.
    Tristearin-d<sub>5</sub>
  • HY-125774S
    Bimatoprost acid-d4
    Bimatoprost acid-d4 (17-Phenyl trinor PGF2α-d4) is the deuterium labeled Bimatoprost acid.
    Bimatoprost acid-d<sub>4</sub>
  • HY-142907S
    (2-Fluoro-4-biphenyl)acetic acid-d5
    		99.64%
    (2-Fluoro-4-biphenyl)acetic acid-d5 is the deuterium labeled (2-Fluoro-4-biphenyl)acetic acid.
    (2-Fluoro-4-biphenyl)acetic acid-d<sub>5</sub>
  • HY-78871S6
    N-Methylpiperazine-d3 hydrochloride
    N-Methylpiperazine-d3 (hydrochloride) is a deuterated labeled N-Methylpiperazine.
    N-Methylpiperazine-d<sub>3</sub> hydrochloride
  • HY-14519S1
    Methotrexate-d3 diammonium
    		99.69%
    Methotrexate-d3 diammonium is the deuterium labeled Methotrexate diammonium. Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).
    Methotrexate-d<sub>3</sub> diammonium
  • HY-B2048S
    Pencycuron-d5
    		99.90%
    Pencycuron-d5 is the deuterium labeled Pencycuron (HY-B2048). Pencycuron is a benzoylurea fungicide. Pencycuron kills fungi by inhibiting the synthesis of fungal cell walls.Pencycuron can be used in research on the control of fungal diseases on crops, such as sheath blight, powdery mildew and late blight.
    Pencycuron-d<sub>5</sub>
  • HY-W244384
    1,3,5-Tribromobenzene-d3
    1,3,5-Tribromobenzene-d3 is the deuterium labeled 1,3,5-Tribromobenzene.
    1,3,5-Tribromobenzene-d<sub>3</sub>
  • HY-W010004S
    1-Bromo-3-chlorobenzene-d4
    1-Bromo-3-chlorobenzene-d4 (3-Chlorobromobenzene-d4) is a deuterium labeled 1-Bromo-3-chlorobenzene.
    1-Bromo-3-chlorobenzene-d<sub>4</sub>
  • HY-Y0444S1
    D-Tyrosine-d4
    		≥99.0%
    D-Tyrosine-d4 is the deuterium labeled D-Tyrosine (HY-Y0444). D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth.
    D-Tyrosine-d<sub>4</sub>
  • HY-W040055S
    Neopterin-13C5
    Neopterin-13C5 (D-(+)-Neopterin-13C5; D-erythro-Neopterin-13C5) is the deuterium labeled Neopterin (HY-W040055). Neopterin (D-(+)-Neopterin), a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation.
    Neopterin-<sup>13</sup>C<sub>5</sub>
  • HY-Y0444S2
    D-Tyrosine-d7
    D-Tyrosine-d7 is the deuterium labeled D-Tyrosine (HY-Y0444). D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth.
    D-Tyrosine-d<sub>7</sub>
  • HY-W700715
    3-Hydroxyoctanoic Acid-d12
    3-Hydroxyoctanoic Acid-d12 is the deuterium labeled 3-Hydroxyoctanoic Acid.
    3-Hydroxyoctanoic Acid-d<sub>12</sub>
  • HY-17413S
    Zidovudine-d3
    Zidovudine-d3 is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.
    Zidovudine-d<sub>3</sub>
  • HY-Y0921S2
    (±)-1,2-Propanediol-d6
    		≥99.0%
    (±)-1,2-Propanediol-d6 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents.
    (±)-1,2-Propanediol-d<sub>6</sub>
  • HY-B0941S
    6-Benzylaminopurine-d5
    		≥98.0%
    6-Benzylaminopurine-d5 is the deuterium labeled 6-Benzylaminopurine. 6-Benzylaminopurine is a cytokinin.
    6-Benzylaminopurine-d<sub>5</sub>