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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9790):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0455S
    Lomefloxacin-d5 hydrochloride
    99.88%
    Lomefloxacin-d5 (hydrochloride) is the deuterium labeled Lomefloxacin hydrochloride. Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin hydrochloride is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc..
    Lomefloxacin-d<sub>5</sub> hydrochloride
  • HY-109506S3
    DPPC-d9-1
    ≥99.0%
    DPPC-d9-1 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice.
    DPPC-d<sub>9</sub>-1
  • HY-N7106S
    Dimethyl phthalate (Ring-d4)
    99.33%
    Dimethyl phthalate (Ring-d4) is the deuterium labeled Dimethyl phthalate. Dimethyl phthalate, a known endocrine disruptor and one of the phthalate esters (PAEs), is a ubiquitous pollutant. Dimethyl phthalate is commonly used as a plasticizer to impart flexibility to rigid polyvinylchloride (PVC) resins.
    Dimethyl phthalate (Ring-d<sub>4</sub>)
  • HY-113301S1
    Hexacosanoic acid-d4-1
    ≥98.0%
    Hexacosanoic acid-d4-11 is the deuterium labeled Hexacosanoic acid (HY-113301). Hexacosanoic acid is a very long-chain fatty acid. Abnormally elevated levels of Hexacosanoic acid are closely associated with various diseases, such as X-linked adrenoleukodystrophy, adrenomyeloneuropathy, atherosclerosis, and dementia.
    Hexacosanoic acid-d<sub>4</sub>-1
  • HY-W040329S1
    2'-Deoxyadenosine-13C10
    ≥99.0%
    2'-Deoxyadenosine-13C10 is 13C-labeled 2'-Deoxyadenosine (HY-W040329). 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer.
    2'-Deoxyadenosine-<sup>13</sup>C<sub>10</sub>
  • HY-W714356
    N-6-Methyl-2-deoxyadenosine-d3
    99.94%
    N-6-Methyl-2-deoxyadenosine-d3 is the deuterium labeled N-6-Methyl-2-deoxyadenosine (HY-W011725). N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue.
    N-6-Methyl-2-deoxyadenosine-d<sub>3</sub>
  • HY-B1438S
    Canrenone-d6
    98.78%
    Canrenone-d6 is the deuterium labeled Canrenone. Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent.
    Canrenone-d<sub>6</sub>
  • HY-W013266S
    N4-Acetylsulfamethoxazole-d4
    98.66%
    N4-Acetylsulfamethoxazole-d4 is the deuterium labeled N4-Acetylsulfamethoxazole. N4-Acetylsulfamethoxazole (Acetylsulfamethoxazole) is a metabolite of?Sulfamethoxazole (HY-B0322). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic, used for bacterial infections.
    N4-Acetylsulfamethoxazole-d<sub>4</sub>
  • HY-B0121BS
    Sumatriptan-d6 succinate
    99.63%
    Sumatriptan-d6 succinate is the deuterium labeled Sumatriptan succinate. Sumatriptan succinate is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for migraine headache research.
    Sumatriptan-d<sub>6</sub> succinate
  • HY-10158S
    Bosutinib-d8
    ≥99.0%
    Bosutinib-d8 is a deuterium labeled Bosutinib. Bosutinib is a dual Src/Abl inhibitor with IC50s of 1.2 nM and 1 nM, respectively.
    Bosutinib-d<sub>8</sub>
  • HY-N0473S6
    L-Tyrosine-3,5-13C2
    99.43%
    L-Tyrosine-3,5-13C2 is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
    L-Tyrosine-3,5-<sup>13</sup>C<sub>2</sub>
  • HY-B1178S1
    (Rac)-Cotinine-d4
    99.56%
    (Rac)-Cotinine-d4 is the deuterium labeled (Rac)-Cotinine.
    (Rac)-Cotinine-d<sub>4</sub>
  • HY-B1776AS
    Spermidine-d8 hydrochloride
    Spermidine-d8 (hydrochloride)e is the deuterium labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents.
    Spermidine-d<sub>8</sub> hydrochloride
  • HY-B0218S
    Orlistat-d3
    Orlistat-d3 is a deuterated labeled Orlistat. Orlistat (Tetrahydrolipstatin) is a well-known irreversible inhibitor of pancreatic and gastric lipases. Orlistat is also an inhibitor of fatty acid synthase (FASN), is used orally for long-term research of obesity.?Anti-atherosclerotic?effect.
    Orlistat-d<sub>3</sub>
  • HY-B0464S
    Hydralazine-d4 hydrochloride
    Hydralazine-d4 hydrochloride is the deuterium labeled Hydralazine hydrochloride. Hydralazine hydrochloride is a direct-acting vasodilator that is used as an antihypertensive agent.
    Hydralazine-d<sub>4</sub> hydrochloride
  • HY-W012908S
    DL-Proline-d7
    DL-Proline-d7 is the deuterium labeled DL-Proline (HY-W012908). H-DL-Pro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    DL-Proline-d<sub>7</sub>
  • HY-119980S
    Fluphenazine-d8
    Fluphenazine-d8 is the deuterium labeled Fluphenazine. Fluphenazine is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine blocks neuronal voltage-gated sodium channels. Fluphenazine acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine can antagonize Methylphenidate-induced stereotyped gnawing and inhibit climbing behaviour in mice. Fluphenazine can be used for researching psychosis and painful peripheral neuropathy associated with diabetes and has potential to inhibit SARS-CoV-2.
    Fluphenazine-d<sub>8</sub>
  • HY-17465S
    Glycopyrrolate-d5 bromide
    Glycopyrrolate-d5 (bromide) is deuterium labeled Glycopyrrolate.
    Glycopyrrolate-d<sub>5</sub> bromide
  • HY-17034AS
    Dexmedetomidine-13C,d3 hydrochloride
    99.93%
    Dexmedetomidine-13C,d3 (hydrochloride) is the 13C- and deuterium labeled Dexmedetomidine (hydrochloride). Dexmedetomidine hydrochloride ((+)-Medetomidine hydrochloride) is a potent, selective and orally active agonist of α2-adrenoceptor, with a Ki of 1.08 nM. Dexmedetomidine hydrochloride shows 1620-fold selectivity against α1-adrenoceptor. Dexmedetomidine hydrochloride exhibits anxiolysis, sedation, and modest analgesia effects.
    Dexmedetomidine-<sup>13</sup>C,d<sub>3</sub> hydrochloride
  • HY-10208S
    Pazopanib-d6
    ≥98.0%
    Pazopanib-d6 is the deuterium labeled Pazopanib. Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.
    Pazopanib-d<sub>6</sub>