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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9898):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W753141
    p,p'-DDE-13C12
    p,p'-DDE-13C12 is 13C labeled p,p'-DDE. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM.
    p,p'-DDE-<sup>13</sup>C<sub>12</sub>
  • HY-150544S
    N-Desmethyl selegiline-d5 hydrochloride
    N-Desmethyl Selegiline-dd5 hydrochloride is the deuterium labeled N-Desmethyl Selegiline hydrochloride. N-Desmethyl Selegiline-d5 hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    N-Desmethyl selegiline-d<sub>5</sub> hydrochloride
  • HY-B0103AS
    (E)-Fluvoxamine-d4 maleate
    (E)-Fluvoxamine-d4 (maleate) is the deuterium labeled (E)-Fluvoxamine maleate[1].
    (E)-Fluvoxamine-d<sub>4</sub> maleate
  • HY-106577S
    Cibenzoline-d4
    Cibenzoline-d4 (Cifenline-d4) is deuterium labeled Cibenzoline. Cibenzoline is a class Ia antiarrhythmic active molecule with low anticholinergic activity. Cibenzoline is a KATP channel inhibitor, acting through the pore forming subunit Kir6.2, with an IC50 of 22.2 μM. Cibenzoline inhibits IKr and IKs currents with IC50 values of 8.8 μM and 12.3 μM, respectively. Cibenzoline is used in the study of cardiac diseases. In addition, Cibenzoline can induce hypoglycemia.
    Cibenzoline-d<sub>4</sub>
  • HY-P0009S1
    Cetrorelix-d10
    Cetrorelix-d10 (SB-75-d10) is deuterium labeled Cetrorelix. Cetrorelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist. Cetrorelix inhibits the endogenous luteinizing hormone surge during ovarian stimulation. Cetrorelix reduces cyclophosphamide induced ovarian follicular destruction in mice.
    Cetrorelix-d<sub>10</sub>
  • HY-N7105S
    γ-Decalactone-d7
    γ-Decalactone-d7 is deuterated labeled γ-Decalactone. γ-Decalactone is a natural flavoring substance with the fruity aroma of juicy peaches. γ-Decalactone can be used as a food additive.
    γ-Decalactone-d<sub>7</sub>
  • HY-132644S1
    3-Demethyl Thiocolchicine--13C2,d6
    3-Demethyl Thiocolchicine---13C2,d6 is 13C and deuterated labeled 3-Demethyl Thiocolchicine-.
    3-Demethyl Thiocolchicine--<sup>13</sup>C<sub>2</sub>,d<sub>6</sub>
  • HY-165640S
    (±)8,9-DiHETrE-d11
    (±)8(9)-DiHET-d11 is deuterium labeled (±)8(9)-DiHET.
    (±)8,9-DiHETrE-d<sub>11</sub>
  • HY-W040193S1
    DSPC-d74
    DSPC-d74 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
    DSPC-d<sub>74</sub>
  • HY-W355238S
    Sec-butyl butyrate-d2
    Sec-butyl butyrate-d2 is deuterated labeled Sec-butyl butyrate.
    Sec-butyl butyrate-d<sub>2</sub>
  • HY-W754640
    Isopropyl 2-hydroxybenzoate-d7
    Isopropyl 2-hydroxybenzoate-d7 (Salicylic acid isopropyl ester-d7) is deuterium labeled Isopropyl 2-hydroxybenzoate.
    Isopropyl 2-hydroxybenzoate-d<sub>7</sub>
  • HY-B2169S2
    Melperone-d4 hydrochloride
    99.84%
    Melperone-d4 hydrochloride is the deuterium labeled Melperone hydrochloride (HY-103109). Melperone hydrochloride is a butyrophenone with atypical antipsychotic properties. Melperone hydrochloride is a multireceptor antagonist with Kds of 102 nM, 180 nM, 180 nM, and 150 nM for 5-HT2A, dopamine D2, α1-adrenergic, and α2-adrenergic receptors, respectively. Melperone hydrochloride has weak binding to histamine H1, 5-HT2C, 5-HT1A, 5-HT1D, and muscarinic receptors, with Kd values ​​of 580 nM, 2100 nM, 2200 nM, 3400 nM, >10000 nM, respectively. Melperone hydrochloride is also a CYP2D6 inhibitor. Melperone hydrochloride can be used for the study of schizophrenia, and agitation in the elderly.
    Melperone-d<sub>4</sub> hydrochloride
  • HY-W275481S1
    5-Octyldihydrofuran-2(3H)-one-d4
    5-Octyldihydrofuran-2(3H)-one-d4 is deuterated labeled 5-Octyldihydrofuran-2(3H)-one.
    5-Octyldihydrofuran-2(3H)-one-d<sub>4</sub>
  • HY-W705331
    Spaglumic acid-d3
    Spaglumic acid-d3 (N-Acetylaspartylglutamic acid-d3) is the deuterium labeled Spaglumic Acid (HY-100921). Spaglumic Acid is a neuropeptide.
    Spaglumic acid-d<sub>3</sub>
  • HY-113068S
    β-Tocopherol-d3
    β-Tocopherol-d3 is the deuterium labeled β-Tocopherol. β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol can also prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol.
    β-Tocopherol-d<sub>3</sub>
  • HY-W004305S
    Hexadecanal-d5
    Hexadecanal-d5 (Palmitaldehyde-d5) is deuterium labeled Hexadecanal. Hexadecanal (Palmitaldehyde) , a volatile long-chain aliphatic aldehyde, is emitted from human feces, skin, and breath. The receptor for hexadecanal(OR37B) is highly conserved across mammals. Hexadecanal may exert its effects by modulating functional connectivity between the brain substrates of social appraisal and the brain substrates of aggressive execution. Also, Hexadecanal is confirmed to be highly deterrent to the ant Lasius niger. Hexadecanal is promising for the research of startle responses and aggression
    Hexadecanal-d<sub>5</sub>
  • HY-158238S
    Silodosin β-D-glucuronide-d4
    Silodosin glucoronide-d4 is deuterium labeled Silodosin glucoronide.
    Silodosin β-D-glucuronide-d<sub>4</sub>
  • HY-13966S3
    2-Deoxy-D-glucose-13C6
    2-Deoxy-D-glucose-13C6 (2-DG-13C6) is 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.
    2-Deoxy-D-glucose-<sup>13</sup>C<sub>6</sub>
  • HY-17503AS1
    Metoprolol-d6 succinate
    Metoprolol-d6 (succinate) is deuterium labeled Metoprolol (succinate). Metoprolol succinate is an orally active, selective β1-adrenoceptor antagonist. Metoprolol succinate shows anti-inflammation, antitumor and anti-angiogenic properties.
    Metoprolol-d<sub>6</sub> succinate
  • HY-U00051AS1
    (R)-Propiomazine-d6 hydrochloride
    (R)-Propiomazine-d6 (hydrochloride) is deuterium labeled Propiomazine (hydrochloride). Propiomazine hydrochloride is an orally active antihistamine agent with sedative effects. Propiomazine hydrochloride can be used in the research of insomnia.
    (R)-Propiomazine-d<sub>6</sub> hydrochloride