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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9979):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-158088S
    N-(1-Oxoheptadecyl)glycine-d2
    N-(1-Oxoheptadecyl)glycine-d2 is the deuterated labeled N-(1-Oxoheptadecyl)glycine.
    N-(1-Oxoheptadecyl)glycine-d<sub>2</sub>
  • HY-B0497S1
    Niclosamide-13C6
    99.0%
    Niclosamide-13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.
    Niclosamide-<sup>13</sup>C<sub>6</sub>
  • HY-W009749AS
    DL-Cystathionine-d4
    99.20%
    DL-Cystathionine-d4 is the deuterium labeled DL-Cystathionine (HY-W009749A). DL-Cystathionine is a mixture of 4 isomers of cystathionine and allocystathionine. DL-Cystathionine also is an intermediate in the biosynthesis of amino acid cysteine.
    DL-Cystathionine-d<sub>4</sub>
  • HY-W654210
    Glycopyrrolate-d3 bromide
    99.63%
    Glycopyrrolate-d3 (bromide) is deuterium labeled Glycopyrrolate. Glycopyrrolate (Glycopyrronium bromide), a quaternary ammonium derivative, is a muscarinic receptor antagonist. Glycopyrrolate has bronchoprotective effect and produces a beneficial effect on blood pressure. Glycopyrrolate can be used for the research of bronchial diseases.
    Glycopyrrolate-d<sub>3</sub> bromide
  • HY-143368S
    L-Phenylmercapturic acid-d5
    99.12%
    L-Phenylmercapturic acid-d5 is the deuterium labeled L-Phenylmercapturic acid (HY-143368). L-Phenylmercapturic acid is often used as a biomarker for exposure to aniline compounds such as aniline and xylene.
    L-Phenylmercapturic acid-d<sup>5</sup>
  • HY-158085S
    N-Undecanoylglycine-d2
    N-Undecanoylglycine-d2 is the deuterated labeled N-Undecanoylglycine.
    N-Undecanoylglycine-d<sub>2</sub>
  • HY-101400S3
    Deoxycytidine triphosphate-15N3 dilithium
    99.0%
    Deoxycytidine triphosphate-15N3 (dCTP-15N3 dilithium; 2′-Deoxycytidine-5′-triphosphate-15N3) dilithium is 15N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
    Deoxycytidine triphosphate-<sup>15</sup>N<sub>3</sub> dilithium
  • HY-W141927S
    N-Heptanoylglycine-d2
    N-Heptanoylglycine-d2 is the deuterated labeled N-Heptanoylglycine (HY-W141927). N-Heptanoylglycine is a Glycine (HY-Y0966) derivative.
    N-Heptanoylglycine-d<sub>2</sub>
  • HY-14805S
    Tecovirimat-d4
    98.95%
    Tecovirimat-d4 (ST-246-d4) is a deuterium-labelled Tecovirimat (HY-14805). Tecovirimat is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus. Tecovirimat could be used in the study for orthopoxvirus-induced diseases.
    Tecovirimat-d<sub>4</sub>
  • HY-B0456S
    Riboflavin-13C4,15N2
    Riboflavin-13C4,15N2is the 13C-labeled and 15N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
    Riboflavin-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-B0357S
    Diclazuril-d4
    98.00%
    Diclazuril-d4 is deuterium labeled Diclazuril. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al.
    Diclazuril-d<sub>4</sub>
  • HY-141642S
    Triheptadecanoin-d5
    99%
    Triheptadecanoin-d5 is the deuterium labeled Triheptadecanoin.
    Triheptadecanoin-d<sub>5</sub>
  • HY-B0246S2
    Carbamazepine-d8
    Carbamazepine-d8 is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant agent, with an IC50 of 131 μM.
    Carbamazepine-d<sub>8</sub>
  • HY-17376S
    Ezetimibe-d4
    98.84%
    Ezetimibe-d4 (SCH 58235-d4) is the deuterium labeled Ezetimibe (HY-17376). Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
    Ezetimibe-d<sub>4</sub>
  • HY-W103882S
    2-(Benzhydrylsulfinyl)acetic acid-d5
    99.59%
    2-(Benzhydrylsulfinyl)acetic acid-d5 is deuterium labeled 2-(Benzhydrylsulfinyl)acetic acid.
    2-(Benzhydrylsulfinyl)acetic acid-d<sub>5</sub>
  • HY-B0144BS
    Pitavastatin-d4 sodium
    99.67%
    Pitavastatin-d4 (sodium) is deuterium labeled Pitavastatin (sodium).
    Pitavastatin-d<sub>4</sub> sodium
  • HY-12779S
    Cyantraniliprole-d3
    99.58%
    Cyantraniliprole-d3 is the deuterium labeled Cyantraniliprole, which is an insecticide of the ryanoid class.
    Cyantraniliprole-d<sub>3</sub>
  • HY-B1773AS
    Sodium propionate-13C
    99.6%
    Sodium propionate-13C is the 13C labeled Propionate sodium (HY-B1773A). Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease.
    Sodium propionate-<sup>13</sup>C
  • HY-B0252S1
    Hydrochlorothiazid-13C,d2
    98.64%
    Hydrochlorothiazid-13C,d2 is the 13C- and deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect.
    Hydrochlorothiazid-<sup>13</sup>C,d<sub>2</sub>
  • HY-B1810S
    Tulobuterol-d9 hydrochloride
    99.0%
    Tulobuterol-d9 (hydrochloride) is the deuterium labeled Tulobuterol. Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength.
    Tulobuterol-d<sub>9</sub> hydrochloride