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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9895):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-124245S2
    3-Hydroxy desloratadine-d6
    3-Hydroxy desloratadine-d6 is deuterated labeled 3-Hydroxy desloratadine (HY-124245). 3-Hydroxy desloratidine is a metabolite of Desloratidine.
    3-Hydroxy desloratadine-d<sub>6</sub>
  • HY-W753602
    Acetamiprid-N-desmethyl-13C,d3
    Acetamiprid-N-desmethyl-13C,d3 is the 13C and deuterium labeled isotope of Acetamiprid-N-desmethyl(13C,d3)(HY-B0823).Acetamiprid is a nAChR agonist that has been implicated in neuromuscular and reproductive disorders.
    Acetamiprid-N-desmethyl-<sup>13</sup>C,d<sub>3</sub>
  • HY-15206S2
    Glibenclamide-13C6
    Glibenclamide-13C6 (Glyburide-13C6) is 13C labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy.
    Glibenclamide-<sup>13</sup>C<sub>6</sub>
  • HY-W032013S3
    1-Octanol-d5
    1-Octanol-d5 is deuterated labeled 1-Octanol (HY-W032013). 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol is a highly attractive biofuel with diesel-like properties.
    1-Octanol-d<sub>5</sub>
  • HY-N0091S4
    Hypoxanthine-13C2,15N-1
    Hypoxanthine-13C2,15N-1 is a 15N-labeled and 13C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
    Hypoxanthine-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N-1
  • HY-B0202S3
    Irbesartan-d7
    Irbesartan-d7 is deuterated labeled Irbesartan (HY-B0202). Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease.
    Irbesartan-d<sub>7</sub>
  • HY-W653929
    Bis(1-chloro-2-propyl) phosphate-d12
    Bis(1-chloro-2-propyl) phosphate-d12 is deuterium labeled Bis(1-chloro-2-propyl) phosphate. Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure.
    Bis(1-chloro-2-propyl) phosphate-d<sub>12</sub>
  • HY-157571S
    N-6-[rel-(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinamine-Sonidegib-d8
    N-6-[rel-(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinamine-Sonidegib-d8 is a stable isotope of hydrazine impurities in Sonidegib (HY-16582A).
    N-6-[rel-(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinamine-Sonidegib-d<sub>8</sub>
  • HY-P5168S
    GPSVFPLAPSSK-13C6,15N2
    GPSVFPLAPSSK-13C6,15N2 is the 13C- and 15N-labeled GPSVFPLAPSSK. GPSVFPLAPSSK is an IgG1 signature peptide of anti-SARS-CoV-2 antibodies. GPSVFPLAPSSK can be used for the quantification of the specific isolation of anti-SARS-CoV-2 antibodies.
    GPSVFPLAPSSK-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-N0504S
    Epi lovastatin-d3
    Epi Lovastatin-d3 is the deuterium labeled Lovastatin. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.
    Epi lovastatin-d<sub>3</sub>
  • HY-N0650S9
    L-Serine-15N,d3
    L-Serine-15N,d3 is the deuterium and 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
    L-Serine-<sup>15</sup>N,d<sub>3</sub>
  • HY-N9484S
    Menthofuran-13C2
    Menthofuran-13C2 is 13C labeled Menthol (HY-N1369). Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca++ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice.
    Menthofuran-<sup>13</sup>C<sub>2</sub>
  • HY-B0411S
    Domperidone-d6
    Domperidone-d6 is the deuterium labeled Domperidone. Domperidone (R33812) is a selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine.
    Domperidone-d<sub>6</sub>
  • HY-W748312
    1,​2,​3,​4,​7,​8,​9-Heptachloro-dibenzofuran-13C12
    1, 2, 3, 4, 7, 8, 9-Heptachloro-dibenzofuran- 13C12 is 13C labeled 1,2,3,4,7,8,9-Heptachlorodibenzo[b,d]furan.
    1,​2,​3,​4,​7,​8,​9-Heptachloro-dibenzofuran-<sup>13</sup>C<sub>12</sub>
  • HY-W012855S
    3-Mercapto-3-methylbutan-1-ol-d6
    3-Mercapto-3-methylbutan-1-ol-d6 is the deuterium labeled 3-Mercapto-3-methylbutan-1-ol.
    3-Mercapto-3-methylbutan-1-ol-d<sub>6</sub>
  • HY-118861AS1
    Clomiphene-d5 citrate
    Clomiphene-d5 (citrate) is the deuterium labeled Enclomiphene citrate. Enclomiphene citrate is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property.
    Clomiphene-d<sub>5</sub> citrate
  • HY-10158S1
    Bosutinib-13C,d3
    Bosutinib-13C,d3 (SKI-606-13C,d3) is 13C labeled Bosutinib. Bosutinib is an orally active Src/Abl tyrosine kinase inhibitor with IC50 of 1.2 nM and 1 nM, respectively.
    Bosutinib-<sup>13</sup>C<sub>,d<sub>3</sub>
  • HY-16973S5
    Fluralaner-d2
    Fluralaner-d2 (A1443-d2) is deuterium labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
    Fluralaner-d<sub>2</sub>
  • HY-132379S
    Hydroxy Pioglitazone-d5 (M-IV) (Mixture of-diastereomers)
    99.17%
    Hydroxy Pioglitazone-d5 (M-IV) (Mixture of-diastereomers) is the deuterium labeled Hydroxy Pioglitazone (M-IV) (Mixture of-diastereomers).
    Hydroxy Pioglitazone-d<sub>5</sub> (M-IV) (Mixture of-diastereomers)
  • HY-170010S
    (E)-5-OAHSA-d17
    (E)-5-OAHSA-d17 is deuterium labeled (E)-5-OAHSA.
    (E)-5-OAHSA-d<sub>17</sub>