Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (2)

Isotope-Labeled Compounds Related Products (9621):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-158088S

N-(1-Oxoheptadecyl)glycine-d₂
N-(1-Oxoheptadecyl)glycine-d₂ is the deuterated labeled N-(1-Oxoheptadecyl)glycine.

HY-B0497S1

Niclosamide-¹³C₆		≥99.0%
Niclosamide-¹³C₆ is the ¹³C₆ labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.

HY-W009749AS

DL-Cystathionine-d₄		99.20%
DL-Cystathionine-d₄ is the deuterium labeled DL-Cystathionine (HY-W009749A). DL-Cystathionine is a mixture of 4 isomers of cystathionine and allocystathionine. DL-Cystathionine also is an intermediate in the biosynthesis of amino acid cysteine.

HY-158085S

N-Undecanoylglycine-d₂
N-Undecanoylglycine-d₂ is the deuterated labeled N-Undecanoylglycine.

HY-101400S3

Deoxycytidine triphosphate-¹⁵N₃ dilithium		≥99.0%
Deoxycytidine triphosphate-¹⁵N₃ (dCTP-¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate-¹⁵N₃) dilithium is ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-W141927S

N-Heptanoylglycine-d₂
N-Heptanoylglycine-d₂ is the deuterated labeled N-Heptanoylglycine (HY-W141927). N-Heptanoylglycine is a Glycine (HY-Y0966) derivative.

HY-122277S

1'-Hydroxy bufuralol-d₉		99.00%
1'-Hydroxy bufuralol-d₉ is a deuterium labeled 1'-Hydroxy bufuralol (HY-122277). 1'-Hydroxy bufuralol, the main metabolite of bufuralol, can reflect CYP2D activity.

HY-107542S

Oleoylethanolamide-d₄		99.00%
Oleoylethanolamide-d₄ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

HY-W017386S

3-Methyl-2-oxovaleric acid-d₈ sodium		99.74%
3-Methyl-2-oxovaleric acid-d₈ sodium is the deuterium labeled 3-Methyl-2-oxovaleric acid. 3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone.

HY-78131S2

Ibuprofen-d₄		99.28%
Ibuprofen-d₄ is a deuterium labeled Ibuprofen (HY-78131). Ibuprofen is a potent, orally active, selective COX-1 inhibitor with an IC₅₀ value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers.

HY-B0134AS

Bestatin-d₇ hydrochloride
Bestatin-d₇ (hydrochloride) is deuterium labeled Bestatin (hydrochloride). Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research.

HY-B0430S

Pantothenic acid-¹³C₃,¹⁵N hemicalcium		99.3%
Pantothenic acid-¹³C₃,¹⁵N (hemicalcium) is the ¹³C-labeled and ¹⁵N-labeled D-Pantothenic acid. D-Pantothenic acid is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism.

HY-I0400S3

N-Acetylneuraminic acid-¹³C-3		≥99.0%
N-Acetylneuraminic acid-¹³C-3 is the ¹³C labeled N-Acetylneuraminic acid.

HY-B0554S

Norethindrone-d₆		98.60%
Norethindrone-d₆ is the deuterium labeled Norethindrone. Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea. Norethindrone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0252S1

Hydrochlorothiazid-¹³C,d₂		98.64%
Hydrochlorothiazid-¹³C,d₂ is the ¹³C- and deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect.

HY-B1810S

Tulobuterol-d₉ hydrochloride		≥99.0%
Tulobuterol-d₉ (hydrochloride) is the deuterium labeled Tulobuterol. Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength.

HY-W242724

1,4-Dibromo-butane-1,1,2,2,3,3,4,4-d₈		99.91%
1,4-Dibromo-butane-1,1,2,2,3,3,4,4-d₈ is the deuterium labeled 1,4-Dibromo-butane.

HY-B0656AS

Rabeprazole-d₄ sodium		98.61%
Rabeprazole-d₄ (sodium) is the deuterium labeled Rabeprazole sodium. Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC₅₀ of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux.

HY-77839S1

Cortodoxone-d₂		99.00%
Cortodoxone-d₂ is the deuterium labeled Cortodoxone. Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).

HY-132960S

N-Propionylglycine-2,2-d₂
N-Propionylglycine-2,2-d₂ is the deuterium labeled N-Propionylglycine-2,2.

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