2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9851):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-10353AS1
    Raltegravir-13C,d3 potassium
    Raltegravir-13C,d3 potassium is 13C labeled Raltegravir potassium (HY-10353A). Raltegravir (MK 0518) potassium is a potent integrase (IN) inhibitor, used to treat HIV infection.
    Raltegravir-<sup>13</sup>C,d<sub>3</sub> potassium
  • HY-150710S
    Cytidine 5'-triphosphate-13C9,15N3 ammonium
    Cytidine 5'-triphosphate-13C9,15N3 (ammonium) is the 13C and 15N labeled Cytidine 5'-triphosphate ammonium.
    Cytidine 5'-triphosphate-<sup>13</sup>C<sub>9</sub>,<sup>15</sup>N<sub>3</sub> ammonium
  • HY-W767399
    8-Bromo-2'-deoxyguanosine-13C,15N2
    8-Bromo-2'-deoxyguanosine-13C,15N2 is the 13C- and 15N-labeled 8-Bromo-2'-deoxyguanosine (HY-W011168). 8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
    8-Bromo-2'-deoxyguanosine-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-124470S
    Amisometradine-d3
    Amisometradine-d3 is the deuterium labeled Amisometradine (HY-124470).
    Amisometradine-d<sub>3</sub>
  • HY-N0717S8
    L-Valine-d1
    L-Valine-d1 ((S)-Valine-d1) is the deuterium labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase.
    L-Valine-d<sub>1</sub>
  • HY-139610S
    3-Sulfo-glycodeoxycholic acid-d4 disodium
    3-Sulfo-glycodeoxycholic acid-d4 (disodium) is the deuterium labeled 3-Sulfo-glycodeoxycholic acid disodium.
    3-Sulfo-glycodeoxycholic acid-d<sub>4</sub> disodium
  • HY-151215S
    S-Sulfo-DL-cysteine-2,3,3-d3-1
    S-Sulfo-DL-cysteine-2,3,3-d3-1 is the deuterium labeled S-Sulfo-DL-cysteine.
    S-Sulfo-DL-cysteine-2,3,3-d<sub>3</sub>-1
  • HY-107337S
    Delapril-d3 hydrochloride
    Delapril-d3 (hydrochloride) is the deuterium labeled Delapril hydrochloride. Delapril hydrochloride is an angiotensin-converting enzyme (ACE) inhibitor for the treatment of cardiovascular diseases.
    Delapril-d<sub>3</sub> hydrochloride
  • HY-119695AS
    Simvastatin acid-d6 ammonium
    Simvastatin acid-d6 (ammonium)mis the deuterium labeled Simvastatin acid ammonium. Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.
    Simvastatin acid-d<sub>6</sub> ammonium
  • HY-W744810
    Ethyl 11(E)-octadecenoate-d5
    Ethyl 11(E)-octadecenoate-d5 (Vaccenic acid ethyl ester-d5) is the deuterium labeled Ethyl 11(E)-octadecenoate (HY-166122). Ethyl 11(E)-octadecenoate is an ester product.
    Ethyl 11(E)-octadecenoate-d<sub>5</sub>
  • HY-W777526
    Nitisinone-13C6
    Nitisinone-13C6 is a 13C-labeled Nitisinone (HY-B0607). Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism.
    Nitisinone-<sup>13</sup>C<sub>6</sub>
  • HY-W753523
    Clorprenaline-d7 hydrochloride
    Clorprenaline-d7 hydrochloride is the deuterium labeled Clorprenaline hydrochloride (HY-B1347). Clorprenaline hydrochloride is a β2-adrenergic receptor agonist that is implicated in bronchial expansion. Clorprenaline has the potential for asthma research.
    Clorprenaline-d<sub>7</sub> hydrochloride
  • HY-Y0226S2
    NSC 1940-d4
    NSC 1940-d4 is the deuterium labeled NSC 1940.
    NSC 1940-d<sub>4</sub>
  • HY-121203S4
    Citalopram-d3 hydrochloride
    Citalopram-d3 hydrochloride is deuterated labeled Citalopram (HY-121203). Citalopram is a racemate mixture of the active S(+)-enantiomer (Escitalopram; HY-14258) and R(-)-enantiomer. Citalopram is an orally active selective serotonin reuptake inhibitor (SSRI). Citalopram is an antidepressant and enhances serotoninergic neurotransmission.
    Citalopram-d<sub>3</sub> hydrochloride
  • HY-146772S
    1-(2-Hydrazinyl-2-oxoethyl)pyridin-1-ium-d5 bromide
    1-(2-Hydrazinyl-2-oxoethyl)pyridin-1-ium-d5 (bromide) is deuterium labeled 1-(2-Hydrazinyl-2-oxoethyl)pyridin-1-ium (bromide).
    1-(2-Hydrazinyl-2-oxoethyl)pyridin-1-ium-d<sub>5</sub> bromide
  • HY-113018S
    Ibuprofen acyl-β-D-glucuronide-d3
    Ibuprofen acyl-β-D-glucuronide-d3 is the deuterium labeled Ibuprofen acyl-β-D-glucuronide.
    Ibuprofen acyl-β-D-glucuronide-d<sub>3</sub>
  • HY-W355043S
    2,3,4,4',5-Pentachloro-1,1'-biphenyl-d4
    2,3,4,4',5-Pentachloro-1,1'-biphenyl-d4 is the deuterium labeled 2,3,4,4',5-Pentachloro-1,1'-biphenyl.
    2,3,4,4',5-Pentachloro-1,1'-biphenyl-d<sub>4</sub>
  • HY-W716999
    Diphenyl Chlorophosphonate-d10
    Diphenyl Chlorophosphonate-d10 is the deuterium labeled Diphenyl chlorophosphate (HY-79353).
    Diphenyl Chlorophosphonate-d<sub>10</sub>
  • HY-167857S
    Glutathione Disulfide-13C4,15N2
    Glutathione Disulfide-13C4,15N2 is the 13C- and 15N-labeled (Rac)-Glutipyran (HY-167857). (Rac)-Glutipyran is a broad-spectrum GLUT inhibitor that targets both GLUT1 and GLUT3. (Rac)-Glutipyran inhibits glucose uptake and suppresses the growth of multiple cancer cells, significantly inhibiting PANC-1 cell growth (IC50=1.8 μM) and glucose uptake (IC50=0.13 μM).
    Glutathione Disulfide-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-14249S1
    Bicalutamide-d5
    Bicalutamide-d5 is deuterated labeled Bicalutamide (HY-14249). Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer.
    Bicalutamide-d<sub>5</sub>