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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9851):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W653877
    Oseltamivir-d3 Phosphate
    Oseltamivir-d3 Phosphate is the deuterium labeled Oseltamivir Phosphate.
    Oseltamivir-d<sub>3</sub> Phosphate
  • HY-W777833
    Ethyl 2-(6-nitro-2,3-dichlorobenzyl)glycine-13C2
    Ethyl 2-(6-nitro-2,3-dichlorobenzyl)glycine-13C2 is the 13C-labeled Ethyl (2,3-dichloro-6-nitrobenzyl)glycinate (HY-W701652).
    Ethyl 2-(6-nitro-2,3-dichlorobenzyl)glycine-<sup>13</sup>C<sub>2</sub>
  • HY-109841S
    Oleoyl Serotonin-d17
    Oleoyl Serotonin-d17 is the deuterium labeled Oleoyl Serotonin.
    Oleoyl Serotonin-d<sub>17</sub>
  • HY-B0203BS2
    (Rac)-Nebivolol-d2,15N
    (Rac)-Nebivolol-d2,15N is 15N and deuterated labeled (Rac)-Nebivolol (HY-B0203B). (Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC50 value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity.
    (Rac)-Nebivolol-d<sub>2</sub>,<sup>15</sup>N
  • HY-W700028
    rac Butoconazole-d5 Nitrate
    rac Butoconazole-d5 Nitrate is the deuterium labeled rac Butoconazole Nitrate.
    rac Butoconazole-d<sub>5</sub> Nitrate
  • HY-B1431S2
    Butylparaben-d9
    Butylparaben-d9 (Butyl parahydroxybenzoate-d9; Butyl paraben-d9) is a deuterium labeled Butylparaben (HY-B1431).
    Butylparaben-d<sub>9</sub>
  • HY-A0014S
    Ramelteon-d5
    Ramelteon-d5 is deuterium labeled Ramelteon. Ramelteon is a potent, highly selective, and orally active agonist of MT1/MT2 with Ki values of 14 and 112 pM, respectively. Ramelteon has the potential for the research of insomnia. Ramelteon consistently reduces sleep onset after long-term treatment, with no next-morning residual effects or rebound insomnia or withdrawal symptoms upon discontinuation.
    Ramelteon-d<sub>5</sub>
  • HY-13443S
    Exendin-4 (Leu-13C6,15N) TFA
    Exendin-4 (Leu-13C6,15N) (Exenatide (Leu-13C6,15N)) TFA is the 13C- and 15N-labeled Exendin-4 TFA (HY-13443). Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM.
    Exendin-4 (Leu-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N) TFA
  • HY-W008364S1
    Olivetol-d9
    Olivetol-d9 is the deuterium labeled Olivetol. Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2[3]. Olivetol also inhibits CYP2C19 and CYP2D6 activities.
    Olivetol-d<sub>9</sub>
  • HY-W654381
    N-Vanillylnonanamide-d3
    N-Vanillylnonanamide-d3 is the deuterium labeled Nonivamide (HY-17568). Nonivamide is a 50 value of 5.1 mg/L in static toxicity tests.
    N-Vanillylnonanamide-d<sub>3</sub>
  • HY-W099504S
    n-Heptyl Alcohol-d15
    n-Heptyl Alcohol-d15 is the deuterium labeled 1-Heptanol.
    n-Heptyl Alcohol-d<sub>15</sub>
  • HY-W012835S3
    4-Methylanisole-d7
    4-Methylanisole-d7 is the deuterium labeled 4-Methylanisole[1]. 4-Methylanisole (4-Methoxytoluene) is food flavoring agent and can be naturally found in Ylang Ylang fragrance oil[2].
    4-Methylanisole-d<sub>7</sub>
  • HY-W748758
    (Z)-Thiothixene-d8
    (Z)-Thiothixene-d8 (NSC 108165-d8; Navan-d8; Navane-d8) is the deuterium labeled Thiothixene (HY-A0139). Thiothixene is a typical antipsychotic. It selectively binds to dopamine D2 over D1, D3, and D4 receptors (Kis=0.417, 338, 186.2, and 363.1 nM, respectively). Thiothixene also binds to various serotonin (5-HT), histamine H1, α1- and α2-adrenergic, muscarinic acetylcholine, and sigma receptors (Kis=15-5,754 nM) as well as the dopamine, norepinephrine, and serotonin transporters (Kis=3.16-30 μM). In vivo, thiothixene reduces spontaneous and amphetamine-induced locomotor activity in rats. It enhances latent inhibition, as measured by a decreased lick latency in response to light and foot shock stimuli, which is a measure of selective attention in rats.3 Thiothixene also increases competitive behavior in submissive mice, indicating antidepressant-like behavior.
    (Z)-Thiothixene-d<sub>8</sub>
  • HY-W740773
    Betamethasone-d10 Dipropionate
    Betamethasone-d10 Dipropionate is the deuterium labeled Betamethasone dipropionate (HY-13571). Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.
    Betamethasone-d<sub>10</sub> Dipropionate
  • HY-132952S
    3-Methylcrotonyl-L-carnitine-d3 chloride
    3-Methylcrotonyl-L-carnitine-d3 (chloride) is the deuterium labeled 3-Methylcrotonyl-L-carnitine chloride.
    3-Methylcrotonyl-L-carnitine-d<sub>3</sub> chloride
  • HY-10353AS1
    Raltegravir-13C,d3 potassium
    Raltegravir-13C,d3 potassium is 13C labeled Raltegravir potassium (HY-10353A). Raltegravir (MK 0518) potassium is a potent integrase (IN) inhibitor, used to treat HIV infection.
    Raltegravir-<sup>13</sup>C,d<sub>3</sub> potassium
  • HY-150710S
    Cytidine 5'-triphosphate-13C9,15N3 ammonium
    Cytidine 5'-triphosphate-13C9,15N3 (ammonium) is the 13C and 15N labeled Cytidine 5'-triphosphate ammonium.
    Cytidine 5'-triphosphate-<sup>13</sup>C<sub>9</sub>,<sup>15</sup>N<sub>3</sub> ammonium
  • HY-W767399
    8-Bromo-2'-deoxyguanosine-13C,15N2
    8-Bromo-2'-deoxyguanosine-13C,15N2 is the 13C- and 15N-labeled 8-Bromo-2'-deoxyguanosine (HY-W011168). 8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
    8-Bromo-2'-deoxyguanosine-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-124470S
    Amisometradine-d3
    Amisometradine-d3 is the deuterium labeled Amisometradine (HY-124470).
    Amisometradine-d<sub>3</sub>
  • HY-N0717S8
    L-Valine-d1
    L-Valine-d1 ((S)-Valine-d1) is the deuterium labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase.
    L-Valine-d<sub>1</sub>