Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (3)

Isotope-Labeled Compounds Related Products (9851):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-131414S5

N-Demethyl vandetanib-d₅
N-Demethyl vandetanib-d₅ is the deuterium labeled N-Demethyl Vandetanib (HY-131414).

HY-146941S

CER8-d₉		≥99.0%
CER8-d₉ is deuterium labeled CER8.

HY-P2625S1

GLP-2(3-33) (Leu-¹³C₆,¹⁵NN) TFA
GLP-2(3-33) (Leu-¹³C₆,¹⁵N) TFA is ¹³C and ¹⁵N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC₅₀=5.8 nM).

HY-146869S

1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d₅ sodium
1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-128753S6

D-Lyxose-d
D-Lyxose-d is the deuterium labeled D-Lyxose. D-Lyxose is an endogenous metabolite.

HY-W745905

2'-Deoxyadenosine-¹⁵N₁
2'-Deoxyadenosine-¹⁵N₁ is the ¹⁵N-labeled 2'-Deoxyadenosine (HY-W040329). 2′-Deoxyadenosine is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine inhibits the growth of various cells. 2'-Deoxyadenosine has an anticancer effect on colon cancer.

HY-113232S

3-Methylcrotonylglycine-d₂
3-Methylcrotonylglycine-d₂ is the deuterium labeled 3-Methylcrotonylglycine. 3-Methylcrotonylglycine is an acyl glycine, a normal amino acid metabolite found in urine.

HY-W777297

Lapatinib-¹³C₂15N
Lapatinib-¹³C₂,¹⁵N Ditosylate is the ¹³C- and ¹⁵N-labeled Lapatinib ditosylate (HY-50898A). Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.

HY-W268193S

Dansyl acid-d₆
Dansyl acid-d₆ is the deuterium labeled Propan-2-amine hydrochloride.

HY-14284S

Nilvadipine-d₄
Nilvadipine-d₄ is deuterium labeled Nilvadipine. Nilvadipine is a potent calcium channel antagonist, and the IC50 value is around 0.1 nM.

HY-B1842S

Fluroxypyr-¹³C₂
Fluroxypyr-¹³C₂ is the ¹³C labled Fluroxypyr (HY-B1842). Fluroxypyr is a herbicide.

HY-D0186S1

2'-Deoxyuridine-2′-¹³C
2'-Deoxyuridine-2′-¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-141925S

3-Octanone-¹³C
3-Octanone-¹³C is the ¹³C labeled 3-Octanone.

HY-W010875S

Didecyl phthalate-d₄
Didecyl phthalate-d₄ is the deuterium labeled Didecyl phthalate.

HY-W754406

6PPD-Quinone methyl ester-d₅
6PPD-Quinone methyl ester-d₅ (Methyl carboxylate 6ppd-quinone-d₅) is the deuterium labeled 6PPD-Quinone methyl ester.

HY-B1267S

Sulfaguanidine-d₄		≥98.0%
Sulfaguanidine-d₄ is the deuterium labeled Sulfaguanidine. Sulfaguanidine, belongs to the class of sulfonamide agent, is an orally active antibiotic. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery.

HY-N7745S2

Glucosylsphingosine-¹³C₆
Glucosylsphingosine-¹³C₆ is an active compound. Glucosylsphingosine-¹³C₆ can be used for various studies.

HY-Y0842S3

Formamide-¹⁵N		99.5%
Formamide-¹⁵N is the ¹⁵N labeled Formamide (HY-Y0842). Formamide is an effective DNA denaturant that significantly reduces the stability of DNA in buffer solutions. Formamide can also be used as a decalcifying agent for rat cardiac cells. Additionally, formamide is widely used as a solvent or chemical raw material for ion compounds, resins, and plasticizers.

HY-B0283S

Acipimox-d₄
Acipimox-d4 is the deuterium labeled Acipimox. Acipimox (K-9321), a nicotinic acid analogue, is an antilipolytic compound. Acipimox acutely inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity.

HY-W777002

Famotidine-¹³C₃
Famotidine-¹³C₃ (MK-208-¹³C₃) is the ¹³C-labeled Famotidine (HY-B0377). Famotidine (MK-208) is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.

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