Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (3)

Isotope-Labeled Compounds Related Products (9851):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-N1096S

3,4-Dimethoxy-benzaldehyde-d₆
3,4-Dimethoxy-benzaldehyde-d₆ is the deuterium labeled Veratraldehyde. Veratraldehyde is an important chemical used in perfumery, agrochemical, and pharmaceutical industries.

HY-B1250S

Acedoben-d₃
Acedoben-d₃ is the deuterium labeled Acedoben.

HY-16561S1

Resveratrol-¹³C₆
Resveratrol-¹³C₆ is the ¹³C-labeled Resveratrol. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator. Resveratrol is a potent pregnane X receptor (PXR) inhibitor. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model. Resveratrol increases production of NO in endothelial cells.

HY-W738320

Carboxyphosphamide Benzyl Ester-d₄
Carboxyphosphamide Benzyl Ester-d₄ is the deuterium labeled Benzyl 3-((amino(bis(2-chloroethyl)amino)phosphoryl)oxy)propanoate (HY-W701421).

HY-146955S

Linoleoyl LPA-d₅
Linoleoyl LPA-d₅ is deuterium labeled Linoleoyl LPA.

HY-17596S

Closantel-¹³C₆
Closantel-¹³C₆ is the ¹³C₆ labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.

HY-16637S4

Folic acid-¹³C₅,¹⁵N
Folic acid-¹⁵N,¹³C₅ is the ¹³C₅ and ¹⁵N labeled Folic acid (HY-16637).

HY-137315S

TML-6-d₃
TML-6-d₃ is the deuterium labeled TML-6. TML-6, an orally active curcumin derivative, inhibits the synthesis of the β-amyloid precursor protein and β-amyloid (Aβ). TML-6 can upregulate Apo E, suppress NF-κB and mTOR, and increase the activity of the anti-

HY-154787S

Descarboethoxyloratadine-d₆ diacetate
Descarboethoxyloratadine-d₆ diacetate is deuterated labeled Descarboethoxyloratadine.

HY-143801S1

N1, N10-Diacetyl triethylenetetramine-d₈
N1, N10-Diacetyl triethylenetetramine-d₈ is the deuterium labeled N1, N10-Diacetyl triethylenetetramine.

HY-W741338

4-(4-Aminophenyl)-3-morpholinone-d₄
4-(4-Aminophenyl)-3-morpholinone-d₄ is the deuterium labeled 4-(4-Aminophenyl)morpholin-3-one (HY-50187).

HY-W744223

(R)-10-Monohydroxy-10,11-dihydro Carbamazepine-d₃
(R)-10-Monohydroxy-10,11-dihydro Carbamazepine-d₃ is the deuterium labeled (R)-10-Monohydroxy-10,11-dihydro Carbamazepine (HY-W739854).

HY-15407S3

Sacubitril-¹³C₄
Sacubitril-13C4 (AHU-377-13C4) is a 13C-labeled version of Sacubitril (HY-15407). Sacubitril is an orally active inhibitor of neprilysin NEP (IC₅₀=5 nM). Sacubitril is used in research on heart failure, hypertension and COVID-19.

HY-N0059AS1

L-(+)-Lyxose-¹³C-1
L-(+)-Lyxose-¹³C-1 is the ¹³C labeled L-Lyxose.

HY-N0667S4

L-Asparagine-4-¹³C monohydrate
L-Asparagine-4-¹³C monohydrate is the ¹³C-labeled L-Asparagine monohydrate (HY-W017443).L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.

HY-B0801S3

Fexofenadine-d₁₀
Fexofenadine-d₁₀ is deuterium labeled Fexofenadine.

HY-14407AS

Fosaprepitant-d₄ dimeglumine
Fosaprepitant-d₄ (dimeglumine) is deuterium labeled Fosaprepitant (dimeglumine). Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV).

HY-B1277AS

Trihexyphenidyl-d₅
Trihexyphenidyl-d₅ is deuterium labeled Trihexyphenidyl.

HY-W423530S

Bis(2-propylheptyl) phthalate-d₄
Bis(2-propylheptyl) phthalate-d₄ (Phthalic acid bis(2-propylheptyl) ester-d₄) is a deuterium labeled compound.

HY-17502S

Simvastatin-d₁₁
Simvastatin-d₁₁ is the deuterium labeled Simvastatin. Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a K_i of 0.2 nM.

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