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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9978):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-10512S
    AR-A014418-d3
    AR-A014418-d3 is the deuterium labeled AR-A014418. AR-A014418 is a potent, selective, and ATP-competitive GSK3β inhibitor (IC50=104 nM; Ki=38 nM).
    AR-A014418-d<sub>3</sub>
  • HY-W048482S2
    rU Phosphoramidite-13C9
    rU Phosphoramidite-13C9 (DMT-2'O-TBDMS-rU phosphoramidite-13C9) is 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
    rU Phosphoramidite-<sup>13</sup>C<sub>9</sub>
  • HY-143986S1
    DM50 impurity 1-d9-1
    DM50 impurity 1-d9-1 is the deuterium labeled DM50 impurity 1.
    DM50 impurity 1-d<sub>9</sub>-1
  • HY-W747877
    Methyl 2-aminoacetate hydrochloride-13C2,15N
    Methyl 2-aminoacetate hydrochloride-13C2,15N is the 13C- and 15N-labeled Methyl 2-aminoacetate hydrochloride (HY-Y1789). Methyl 2-aminoacetate hydrochloride is a Glycine (HY-Y0966) derivative.
    Methyl 2-aminoacetate hydrochloride-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-W017540S
    Cyclocreatine-13C3
    Cyclocreatine-13C3 is the 13C-labeled Cyclocreatine (HY-W017540). Cyclocreatine, a creatine analogue, acts as a brain-penetrant and potent bioenergetic protective agent by providing high levels of ATP. Cyclocreatine can be phosphorylated and dephosphorylated by creatine kinases. Cyclocreatine suppresses creatine metabolism ameliorating the cognitive, autistic and epileptic phenotype in a mouse model of creatine transporter defciency. Cyclocreatine protects against ischemic injury and enhances cardiac recovery during early reperfusion in dogs and rats. Cyclocreatine decreases plaque-adjacent neuronal dystrophy in TREM2-deficient mice with amyloid-β pathology. Cyclocreatine is proming for research of ischemic heart disease, cardiovascular diseases, Alzheimer’s disease and other neurodegenerative diseases associated with microglial dysfunction, prostate cancer.
    Cyclocreatine-<sup>13</sup>C<sub>3</sub>
  • HY-W748582
    Clozapine N-oxide-d8
    Clozapine N-oxide-d8 is the deuterium labeled Clozapine N-oxide (HY-17366). Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide can't cross the blood-brain barrier. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist.
    Clozapine N-oxide-d<sub>8</sub>
  • HY-143929S
    Bazedoxifene-5-glucuronide-d4
    Bazedoxifene-5-glucuronide-d4 is the deuterium labeled Bazedoxifene-5-glucuronide.
    Bazedoxifene-5-glucuronide-d<sub>4</sub>
  • HY-B0084S
    Dienogest-d4
    Dienogest-d4 is deuterium labeled Dienogest.
    Dienogest-d<sub>4</sub>
  • HY-W767389
    Androsterone glucuronide-d5
    Androsterone glucuronide-d5 is the deuterium labeled Androsterone glucuronide (HY-113104).
    Androsterone glucuronide-d<sub>5</sub>
  • HY-W747751
    Sorbic acid-13C2
    Sorbic acid-13C2 is the 13C-labeled Sorbic acid (HY-N0626). Sorbic acid is an effective, safe, and non-toxic food preservative. It can effectively inhibit most molds, yeasts, and certain bacteria. Sorbic acid is orally active and can enhance the growth performance of economically important animals (Duroc × Landrace × Yorkshire piglets) by activating the insulin-like growth factor system (IGF), and it can also lead to lipid accumulation by disrupting lipid clearance pathways.
    Sorbic acid-<sup>13</sup>C<sub>2</sub>
  • HY-40161S
    Indole-3-carboxylic acid-d4
    Indole-3-carboxylic acid-d4 is deuterium labeled Indole-3-carboxylic acid. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases.
    Indole-3-carboxylic acid-d<sub>4</sub>
  • HY-I1129
    Fmoc-3VVD-OH-d8
    Fmoc-3VVD-OH-d8 is a deuterium labeled Fmoc-3VVD-OH (HY-78921). Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
    Fmoc-3VVD-OH-d<sub>8</sub>
  • HY-Y1166S
    N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester-13C5,15N
    N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester-13C5,15N is the 13C-labeled and 15N-labeled N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester (HY-Y1166). N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester is a glutamic acid derivative.
    N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N
  • HY-W767001
    Delmadinone-d5
    Delmadinone-d5 (Δ1-Chlormadinone-d5) is the deuterium labeled Delmadinone (HY-105757).
    Delmadinone-d<sub>5</sub>
  • HY-W769319
    Inosinic acid-13C5
    Inosinic acid-13C5 (5'-IMP-13C5) is the 13C-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs.
    Inosinic acid-<sup>13</sup>C<sub>5</sub>
  • HY-W778288
    (±)-Enterodiol-13C3
    (±)-Enterodiol-13C3 is the 13C-labeled (±)-Enterodiol (HY-108695B). (±)-Enterodiol is the racemate of Enterodiol (HY-108695). Enterodiol is transformed by human intestinal bacteria from lignans contained in various whole-grain cereals, nuts, legumes, flaxseed, and vegetables. Enterodiol has an apoptotic effect in colorectal cancer (CRC) cells. Enterodiol has anti-cancer activities.
    (±)-Enterodiol-<sup>13</sup>C<sub>3</sub>
  • HY-166922S
    2,3,4,5-Tetrachloro-4′-methoxy biphenyl-13C12
    2,3,4,5-Tetrachloro-4′-methoxy biphenyl-13C12 is 13C labeled 2,3,4,5-Tetrachloro-4′-methoxy biphenyl.
    2,3,4,5-Tetrachloro-4′-methoxy biphenyl-<sup>13</sup>C<sub>12</sub>
  • HY-W743007
    Peramine Hydrochloride Salt-d3
    Peramine Hydrochloride Salt-d3 is the deuterium labeled Peramine Hydrochloride Salt.
    Peramine Hydrochloride Salt-d<sub>3</sub>
  • HY-W269867S
    Tetratriacontane-d70
    Tetratriacontane-d70 is the deuterium labeled Tetratriacontane.
    Tetratriacontane-d<sub>70</sub>
  • HY-W001942S
    DL-2-Methyl-d3-butyric acid
    DL-2-Methyl-d3-butyric acid is the deuterium labeled DL-2-Methyl-butyric acid.
    DL-2-Methyl-d<sub>3</sub>-butyric acid