Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitor (1)

Isotope-Labeled Compounds Related Products (7658):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-B0435S

Roxithromycin-d₇		98.28%
Roxithromycin-d₇ (RU-28965-d₇) is the deuterium labeled Roxithromycin (HY-B0435). Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

HY-100808S

D-Serine-d₃
D-Serine-d₃ ((R)-Serine-d₃) is a deuterium labeled D-Serine (HY-100808). D-Serine ((R)-Serine), an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. D-Serinee has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration.

HY-B0617S2

S-Adenosyl-L-methionine-¹³C dihydrochloride
S-Adenosyl-L-methionine-¹³C (S-Adenosyl methionine-¹³C) dihydrochloride is the ¹³C labeled S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine (S-Adenosyl methionine) is an orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine has the potential for, cancer, liver disease and osteoarthritis research.

HY-W004260S4

Arachidic acid-d₄		99.20%
Arachidic acid-d₄ is the deuterium labeled Arachidic acid. Arachidonic acid (Icosanoic acid), a long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant polyunsaturated fatty acids present in human tissue[1][2].

HY-34449S

Methylboronic acid-d₃
Methylboronic acid-d₃ is the deuterium labeled Methylboronic acid (HY-34449). Methylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-B0215S

Acetylcysteine-d₃
Acetylcysteine-d₃ is the deuterium labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies.

HY-W009749CS

(S)-Cystathionine-d₄
(S)-Cystathionine-d₄ is the deuterium labeled (S)-Cystathionine[1].

HY-W013049S3

Docosanoic acid-d₃		99.79%
Docosanoic acid-d₃ (Behenic acid-d₃) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a K_d of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans.

HY-13740S

Resiquimod-d₅		99.84%
Resiquimod-d₅ is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α.

HY-N1424S

Glycoursodeoxycholic Acid-d₄		98.88%
Glycoursodeoxycholic acid-d4 (Ursodeoxycholylglycine-d4) is the deuterium labeled Glycoursodeoxycholic acid. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid[1][2].

HY-17589AS

Chloroquine-d₅		99.90%
Chloroquine-d₅ is deuterium labeled Chloroquine (HY-17589A). Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC₅₀=1.13 μM).

HY-Y0248AS

(E,E)-Farnesol-d₆		98.56%
(E,E)-Farnesol-d₆ is deuterium labeled Farnesol. Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria.

HY-N0402S

Artemether-d₃		≥99.0%
Artemether-d₃ is the deuterium labeled Artemether. Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.

HY-132643S

Benzyldimethyltetradecylammonium-d₇ chloride
Benzyldimethyltetradecylammonium-d₇ (chloride) is the deuterium labeled Benzyldimethyltetradecylammonium chloride[1].

HY-B0535S

Ethambutol-d₄		98.12%
Ethambutol-d₄ is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

HY-N0570S

Hydroxytyrosol-d₄
Hydroxytyrosol-d₄ is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].

HY-10261S

Afatinib-d₆		≥99.0%
Afatinib-d₆ is deuterium labeled Afatinib. Afatinib (BIBW 2992) is an irreversible EGFR family inhibitor[1].

HY-132421S

(±)-Equol-d₄		99.79%
(±)-Equol-d₄ is the deuterium labeled (±)-Equol[1].

HY-136406S

Bongkrekic acid-¹³C₂₈		≥98.0%
Bongkrekic acid-¹³C₂₈ is the ¹³C labeled Bongkrekic acid (HY-136406). Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport.

HY-Y0688S

1H-Benzotriazole-4,5,6,7-d₄		99.83%
1H-Benzotriazole-4,5,6,7-d₄ is the deuterium labeled 1H-Benzo[d][1,2,3]triazole[1].

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