2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9852):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W654066
    Beclomethasone 17-Propionate-d5
    Beclomethasone 17-Propionate-d5 is deuterated labeled Beclomethasone 17-Propionate.
    Beclomethasone 17-Propionate-d<sub>5</sub>
  • HY-W705769
    (Z)-4-(Methoxy-d3)-4-oxobut-2-enoic acid
    (Z)-4-(Methoxy-d3)-4-oxobut-2-enoic acid is the deuterium labeled Monomethyl maleate (HY-W129396).
    (Z)-4-(Methoxy-d<sub>3</sub>)-4-oxobut-2-enoic acid
  • HY-N6801S
    Nivalenol-13C15
    Nivalenol-13C15 is the 13C labeled Nivalenol (HY-N6801). Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product. Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect.
    Nivalenol-<sup>13</sup>C<sub>15</sub>
  • HY-146763S
    N-Tridecanoyl-D-erythro-sphinganine-d7
    N-Tridecanoyl-D-erythro-sphinganine-d7 is deuterium labeled N-Tridecanoyl-D-erythro-sphinganine.
    N-Tridecanoyl-D-erythro-sphinganine-d<sub>7</sub>
  • HY-W339957S
    2,6-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5
    2,6-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5 is the deuterium labeled 2,6-Dichloro-1,1'-biphenyl.
    2,6-Dichlorobiphenyl-2′,3′,4′,5′,6′-d<sub>5</sub>
  • HY-17504AS
    Rosuvastatin-d3
    Rosuvastatin-d3 is a deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals.
    Rosuvastatin-d<sub>3</sub>
  • HY-B1971S
    Deltamethrin-d5
    Deltamethrin-d5 is the deuterium labeled Deltamethrin. Deltamethrin (Decamethrin), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.
    Deltamethrin-d<sub>5</sub>
  • HY-W034097S
    trans-Trismethoxy Resveratrol-d4
    trans-Trismethoxy Resveratrol-d4 is the deuterium labeled trans-Trismethoxy Resveratrol.
    trans-Trismethoxy Resveratrol-d<sub>4</sub>
  • HY-B0215S1
    Acetylcysteine-15N
    Acetylcysteine-15N (N-Acetylcysteine-15N) is the 15N-labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies.
    Acetylcysteine-<sup>15</sup>N
  • HY-14874S
    Topiroxostat-d4
    Topiroxostat-d4 is deuterium labeled Topiroxostat. Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7 nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment.
    Topiroxostat-d<sub>4</sub>
  • HY-W654296
    Octocrylene-13C3
    Octocrylene-13C3 is the 13C-labeled Octocrylene (HY-A0087). Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes.
    Octocrylene-<sup>13</sup>C<sub>3</sub>
  • HY-13272S3
    Dacomitinib-d10
    Dacomitinib-d10 is deuterium labeled Dacomitinib. Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively.
    Dacomitinib-d<sub>10</sub>
  • HY-W283596S
    p-Azoxyanisole-d6
    p-Azoxyanisole-d6 is the deuterium labeled p-Azoxyanisole.
    p-Azoxyanisole-d<sub>6</sub>
  • HY-100935S
    Cimaterol-d7
    Cimaterol-d7 is the deuterium labeled Cimaterol. Cimaterol is a potent agonist of β-adrenergic receptors (pEC50s=8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively). Cimaterol has been used in farmed animals to increase carcass mass and to alter muscle and fat deposition.
    Cimaterol-d<sub>7</sub>
  • HY-A0024AS1
    (Rac)-Tolterodine-d5
    (Rac)-Tolterodine-d5 is deuterium labeled (rac)-Tolterodine.
    (Rac)-Tolterodine-d<sub>5</sub>
  • HY-146905S
    CER6-2’S-d9
    		≥99.0%
    CER6-2’S-d9 is deuterium labeled CER6-2’S.
    CER6-2’S-d<sub>9</sub>
  • HY-W777156
    Carazolol-d6 hydrochloride
    Carazolol-d6 (hydrochloride) is deuterium labeled Carazolol hydrochloride (HY-W517264). Carazolol hydrochloride is a highly potent antagonist of β1/β2 adrenoceptor. Carazolol hydrochloride is also a potent, selective β3-adrenoceptor agonist. Carazolol hydrochloride can be used in the research of hypertension.
    Carazolol-d<sub>6</sub> hydrochloride
  • HY-B1622S
    Cyproheptadine-d3
    Cyproheptadine-d3 is deuterium labeled Cyproheptadine.
    Cyproheptadine-d<sub>3</sub>
  • HY-N7092S18
    D-Fructose-d2-1
    D-Fructose-d2-1 is the deuterium labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
    D-Fructose-d<sub>2</sub>-1
  • HY-W009512S
    CVT-2738-d8
    N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide-d8 is the deuterium labeled N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide.
    CVT-2738-d<sub>8</sub>