2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9852):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0005AS
    Toremifene-d6
    Toremifene-d6 is deuterium labeled Toremifene. Toremifene (Z-Toremifene) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.07 μM and 2.6 μM, respectively.
    Toremifene-d<sub>6</sub>
  • HY-B0670S
    Dihydroergotamine-d3
    Dihydroergotamine-d3 is deuterium labeled Dihydroergotamine (hydrochloride).
    Dihydroergotamine-d<sub>3</sub>
  • HY-14598S1
    Diethylstilbestrol-d3
    Diethylstilbestrol-d3 is deuterium labeled Diethylstilbestrol.
    Diethylstilbestrol-d<sub>3</sub>
  • HY-145004S
    (±)8,9-DiHETrE-d11
    (±)8,9-DiHETrE-d11 is the deuterium labeled (±)8,9-DiHETrE.
    (±)8,9-DiHETrE-d<sub>11</sub>
  • HY-13623S1
    Entecavir-13C2,15N
    Entecavir-13C2,15N (BMS200475-13C2,15N; SQ34676-13C2,15N) is a 13C- and 15N-labeled Entecavir (HY-13623). Entecavir (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.
    Entecavir-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-143977S
    Loxapine impurity 3-d8 iodide
    Loxapine impurity 3-d8 (iodide) is the deuterium labeled Loxapine impurity 3 iodide.
    Loxapine impurity 3-d<sub>8</sub> iodide
  • HY-172733S
    PRMT5-MTA-IN-3-d3
    PRMT5-MTA-IN-3-d3 (compound P22) is the deuterium labeled PRMT5-MTA-IN-3 (HY-172733). PRMT5-MTA-IN-3-d3 is an orally active PRMT5-MTA inhibitor. PRMT5-MTA-IN-3-d3 has antiproliferative effects on HTC116-MTAP del and wild type colorectal cancer HCT-116 cell lines, with IC50 values of 6 nM and 961 nM, respectively. PRMT5-MTA-IN-3-d3 has anticancer effects, especially for MTAP-deficient tumors, such as non-small cell lung cancer (NSCLC), pancreatic cancer.
    PRMT5-MTA-IN-3-d<sub>3</sub>
  • HY-A0132S9
    N-Acetyl-D-glucosamine-13C3,15N
    N-Acetyl-D-glucosamine-13C3,15N is the 13C and 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc.
    N-Acetyl-D-glucosamine-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N
  • HY-17037S1
    Pirenzepine-d8 dihydrochloride
    Pirenzepine-d8 (LS 519-d8; Pirenzepin-d8) dihydrochloride is a deuterium labeled Pirenzepine (dihydrochloride) (HY-17037). Pirenzepine (LS 519) dihydrochloride is a selective M1 mAChR (muscarinic acetylcholine receptor) antagonist. Pirenzepine dihydrochloride reduces gastric acid secretion and reduces muscle spasm, can be used in peptic ulcers research. Pirenzepine dihydrochloride shows anti-proliferative activity to cancer cells.
    Pirenzepine-d<sub>8</sub> dihydrochloride
  • HY-113400S
    Cytidine diphosphate-15N3 dilithium
    Cytidine diphosphate-15N3 dilithium is 15N labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
    Cytidine diphosphate-<sup>15</sup>N<sub>3</sub> dilithium
  • HY-B0125AS
    Ofloxacin-d8 hydrochloride
    Ofloxacin-d8 (hydrochloride) is deuterium labeled Ofloxacin (hydrochloride).
    Ofloxacin-d<sub>8</sub> hydrochloride
  • HY-W750488
    Glycolithocholic acid-d5
    Glycolithocholic acid-d5 (Lithocholylglycine-d5) is the deuterium labeled Glycolithocholic acid (HY-116374). Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC).
    Glycolithocholic acid-d<sub>5</sub>
  • HY-100441S3
    Treprostinil-d7
    Treprostinil-d7 (UT-15-d7) is a deuterated version of Treprostinil (HY-100441). Treprostinil is a highly potent DP1 and EP2 agonist with EC50s of 0.6 nM and 6.2 nM, respectively.
    Treprostinil-d<sub>7</sub>
  • HY-116214S1
    Cyprodinil-13C6
    Cyprodinil-13C6 (CGA-219417-13C6) is the 13C6 labeled Cyprodinil (HY-116214). Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens.
    Cyprodinil-<sup>13</sup>C<sub>6</sub>
  • HY-W778791
    N-Formylglycine ethyl ester-13C2
    N-Formylglycine ethyl ester-13C2 is the 13C-labeled N-Formylglycine Ethyl Ester (HY-W141893). N-Formylglycine Ethyl Ester is a Glycine (HY-Y0966) derivative.
    N-Formylglycine ethyl ester-<sup>13</sup>C<sub>2</sub>
  • HY-W768571
    Pseudouridine-13C,15N2
    Pseudouridine-13C,15N2 is the 13C- and 15N-labeled Pseudouridine (HY-113061). Pseudouridine is an isomer of uridine and the most abundant modified nucleoside in non-coding RNA. It fine-tunes and stabilizes regional structures in rRNA and tRNA, maintaining their functions in mRNA decoding, ribosome assembly, processing, and translation. Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis and hold promise for research on myelodysplastic syndrome (MDS)-related leukemia..
    Pseudouridine-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-W017408S
    Methyl 3-aminobenzoate-d4
    Methyl 3-aminobenzoate-d4 is the deuterium labeled Methyl 3-aminobenzoate.
    Methyl 3-aminobenzoate-d<sub>4</sub>
  • HY-W740569
    3-Acetopropanol-d4
    3-Acetopropanol-d4 is the deuterium labeled 5-Hydroxy-2-pentanone (HY-34405).
    3-Acetopropanol-d<sub>4</sub>
  • HY-10163AS1
    Dabigatran-d5 hydrochloride
    Dabigatran-d5 (hydrochloride) is the deuterium labeled Dabigatran hydrochloride.
    Dabigatran-d<sub>5</sub> hydrochloride
  • HY-150612S
    (R)-STU104-d6
    (R)-STU104-d6 is a deuterium labeled (R)-STU104 (HY-150612). (R)-STU104 is a potent and orally active TAK1-MKK3 interaction inhibitor with IC50s of 0.58 μM and 4.0 μM for TNF-α and MKK3 phosphorylation. (R)-STU104 suppresses the TAK1/MKK3/p38/MnK1/MK2/elF4E signal pathways through binding with MKK3 and disrupting the TAK1 phosphorylating MKK3. (R)-STU104 can be used for researching ulcerative colitis.
    (R)-STU104-d<sub>6</sub>