Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitor (1)

Isotope-Labeled Compounds Related Products (7657):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W017018S2

L-Ornithine-1,2,3,4,5-¹³C₅ hydrochloride		99.5%
L-Ornithine-1,2,3,4,5-¹³C₅ (hydrochloride) is the ¹³C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-146633S

24(RS)-Hydroxycholesterol-d₇		98.63%
24(RS)-Hydroxycholesterol-d₇ is the deuterium labeled 24(RS)-Hydroxycholesterol[1].

HY-133152S

Brexpiprazole S-oxide-d₈		98.72%
Brexpiprazole S-oxide-d₈ is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4). Brexpiprazole is an atypical antipsychotic agent and a partial agonist of human 5-HT1A and dopamine receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM[1][2][3].

HY-13966S

2-Deoxy-D-glucose-d		≥98.0%
2-Deoxy-D-glucose-d is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].

HY-B0158S7

Cytidine-¹³C₉
Cytidine-¹³C9 (Cytosine β-D-riboside-¹³C9; Cytosine-1-β-D-ribofuranoside-¹³C9) is ¹³C labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function.

HY-113150S1

Hexanoylglycine-d₂		≥98.0%
Hexanoylglycine-d₂ is the deuterium labeled Hexanoylglycine[1].

HY-W004261S

Nonadecanoic acid-d₃₇		≥98.0%
Nonadecanoic acid-d₃₇ is the deuterium labeled Nonadecanoic acid. Nonadecanoic acid is a 19-carbon long saturated fatty acid. Nonadecanoic acid is the major constituent of the substance secreted by Rhinotermes marginalis to defence[1].

HY-16305S

Maribavir-d₆		99.75%
Maribavir-d₆ (1263W94-d₆) is a deuterium labeled Maribavir (HY-16305). Maribavir is a potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro, with an IC₅₀ of 3 nM.

HY-113478S

Ursodeoxycholic acid-2,2,4,4-d₄		99.52%
Ursodeoxycholic acid-2,2,4,4-d₄ is the deuterium labeled Ursodeoxycholic acid (HY-13771). Ursodeoxycholic acid is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection[1][2][3][4][5].

HY-113225S5

Guanosine triphosphate-¹³C₁₀ dilithium
Guanosine triphosphate-¹³C₁₀ (GTP-¹³C₁₀) dilithium is ¹³C-labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.

HY-W040193S

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₇₀		≥99.0%
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₇₀ is the deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].

HY-14865S

Omadacycline-d₉		99.21%
Omadacycline-d9 (PTK 0796-d9; Amadacycline-d9) is the deuterium labeled Omadacycline (HY-14865) that can be used as the internal standard for the analysis of Omadacycline.

HY-N0623S7

L-Tryptophan-¹⁵N		98.62%
L-Tryptophan-¹⁵N is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N1429S1

Taurochenodeoxycholic acid-d₅ sodium		98.12%
Taurochenodeoxycholic acid-d₅ (sodium) is the deuterium labeled Taurochenodeoxycholic acid sodium. Taurochenodeoxycholic acid sodium salt (12-Deoxycholyltaurine sodium salt) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties[1][2].

HY-B0389S

D-Glucose-¹³C₆,d₇		≥98.0%
D-Glucose-¹³C₆,d₇ is the deuterium and ¹³C labeled D-Glucose[1].

HY-N0658S

L-Threonine-¹⁵N		≥98.0%
L-Threonine-¹⁵N is the ¹⁵N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1][2].

HY-W142820S

1,1,3,3-Tetraethoxypropane-d₂
1,1,3,3-Tetraethoxypropane-d₂ is the deuterium labeled 1,1,3,3-Tetraethoxypropane[1].

HY-N0230S2

β-Alanine-d₄		99.90%
β-Alanine-d₄ is the deuterium labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.

HY-50936S

Trabectedin-d₃		99.08%
Trabectedin D3 (Ecteinascidin 743 D3) is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has tje potential for soft tissue sarcoma and ovarian cancer treatment.

HY-W004260S2

Arachidic acid-d₃
Arachidic acid-d₃) is the deuterium labeled Arachidic acid. Arachidonic acid (Icosanoic acid), a long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant polyunsaturated fatty acids present in human tissue[1][2].

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