2. Signaling Pathways
  3. Immunology/Inflammation
  4. IKZF Family
  5. IKZF1 Isoform
  6. IKZF1 Inhibitor

IKZF1 Inhibitor

IKZF1 Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-145776
    ALV1
    		Inhibitor 98.62%
    ALV1 is a molecular glue degrader for Ikaros (IKZF1) and Helios (IKZF2) with DC50 of 2.5 nM and 10.3 nM respectively. ALV1 bind CRBN with an IC50 of 0.55 μM, and induces CRBN-Helios dimerization. ALV1 can be used to study the properties and functions of regulatory T cells.