2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
    Neuronal Signaling
  4. iGluR
  5. Kainate Receptor Isoform
  6. Kainate Receptor Agonist

Kainate Receptor Agonist

Kainate Receptor Agonists (2):

Cat. No. Product Name Effect Purity
  • HY-101310
    SYM 2081
    		Agonist ≥98.0%
    SYM 2081 is a kainate receptor agonist. SYM 2081 is a substrate of EAAT1 (Km of 54 μM). SYM 2081 inhibits EAAT2-mediated glutamate transport (Kb is 3.4 μM in Xenopus oocytes), modulates Apoptotic signaling pathways (increases Bcl-2 and decreases Bax/caspase-3 expression). SYM 2081 exhibits neuroprotective activity. SYM 2081 can be used in the study of hypoxic-ischemic brain damage and inflammatory or neuropathic pain.
  • HY-12499
    (S)-Willardiine
    		Agonist 98.93%
    (S)-Willardiine is a potent agonist of AMPA/kainate receptors with EC50 of 44.