2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D2148
    AF 430 tetrazine
    AF 430 tetrazine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. To achieve specific coupling of dye labels and biomolecules.
    AF 430 tetrazine
  • HY-D0934
    (5)6-Carboxytetramethylrhodamine
    		98.29%
    (5)6-Carboxytetramethylrhodamine contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; bright, orange-fluorescent dye produces conjugates with absorption/emission maxima of ~555/580 nm.
    (5)6-Carboxytetramethylrhodamine
  • HY-155062
    IR-251
    IR-251 is a mitochondrion-targeting NIR fluorescent probe. IR-251 targets mitochondria via OATPs and causes mitochondrial damage in tumor cells. IR-251 IR-251 induced ROS overproduction by inhibiting PPARγ, and then inhibiting the β-catenin signaling pathway and downstream protein molecules related to the cell cycle and metastasis. IR-251 inhibits tumor proliferation and metastasis.
    IR-251
  • HY-D1922
    ATTO 390 streptavidin
    ATTO 390 streptavidin is a streptavidin derivative of ATTO 390 with excitation/emission maxima at 390/476 nm.
    ATTO 390 streptavidin
  • HY-D1299
    meso-CF3-BODIPY 2
    meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) is a fluorescent dye with the absorption wavelength (λabs) of 553 nm and emission wavelength (λem) of 622 nm. meso-CF3-BODIPY 2 can be used in labeling reagents and photodynamic therapy.
    meso-CF3-BODIPY 2
  • HY-D1098A
    SYBR Green II (Ionic form)
    SYBR Green II (Ionic form) is a fluorescent nucleic acid dye that mainly binds single-stranded nucleotides. SYBR Green II is sensitive to oligonucleotides or larger nucleic acid polymers in a variety of cells and gels. SYBR Green II can be used to study cell structure, membrane integrity or function, and cell cycle distribution. Wavelength 484/515 nm.
    SYBR Green II (Ionic form)
  • HY-D0554
    Sumitone fast red b
    Sumitone fast red b is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Sumitone fast red b
  • HY-131772
    2-AHA-cAMP
    2-AHA-cAMP is an analogue of natural signal molecule cAMP and an activator of cAMP-dependent protein kinase. 2-AHA-cAMP has a free terminal primary amino group, which can be used for coupling to gels or fluorescent dyes.
    2-AHA-cAMP
  • HY-D2844B
    FITC-PEG-FA (MW 2000)
    FITC-PEG-FA (MW 2000) is a fluorescent dye composed of Folic acid (HY-16637) (FA), polyethylene glycol (PEG) and FITC (HY-66019). Fluorescent dye is linked to PEG and Folic acid through a specific chemical reaction to form a molecule with special properties. FITC-PEG-FA (MW 2000) can be used for fluorescent labeling and imaging.
    FITC-PEG-FA (MW 2000)
  • HY-D2824
    Chitosan-Cy7.5 (MW 10000)
    Chitosan-Cy7.5 (MW 10000) is a Chitosan labeled with Cy7.5 (HY-D0926). Chitosan-Cy7.5 (MW 10000) can be used for fluorescent labeling and imaging.
    Chitosan-Cy7.5 (MW 10000)
  • HY-137791
    MMBC
    MMBC is a sulfhydryl-sensitive fluorophore.
    MMBC
  • HY-D2033
    ATTO 514 azide
    ATTO 514 azide is an azide derivative of ATTO 514 with excitation/emission maxima at 511/531 nm. ATTO 514 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    ATTO 514 azide
  • HY-D1330
    BDP R6G azide
    BDP R6G azide is an anlong of BDP dye. BDP R6G azide is available that are tuned to match excitation and emission channels of classical xanthene and cyanine dyes. BDP R6G azide can be used in copper-catalyzed Click chemistry reactions with alkynes, DBCO and BCN. (λex=530 nm, λem=548 nm).
    BDP R6G azide
  • HY-D2826B
    FITC-Chitosan (MW 20000)
    FITC-Chitosan (MW 20000) is a Chitosan labeled with FITC (HY-66019). FITC-Chitosan (MW 20000) can be used for fluorescent labeling and imaging.
    FITC-Chitosan (MW 20000)
  • HY-D2892A
    Rhodamine-PEG (MW 550)
    Rhodamine-PEG (MW 550) a fluorescent PEG derivative composed of Rhodamine B (HY-Y0016) and PEG. Rhodamine-PEG (MW 550) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm).
    Rhodamine-PEG (MW 550)
  • HY-151536
    meso-Benzothiazole-BODIPY 505/515
    meso-Benzothiazole-BODIPY 505/515 is a boron dipyrromethenes (BODIPY) -based fluorescent probeautophagy. meso-Benzothiazole-BODIPY 505/515 can be used for the research of Alzheimer’s diseases, lysosomal storage diseases and neural degeneration diseases.
    meso-Benzothiazole-BODIPY 505/515
  • HY-D1139
    Pigment red 177
    Pigment Red 177 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.
    Pigment red 177
  • HY-103684
    RT-NH2
    RT-NH2 is a RealThiol prototype without the carboxylic acid groups. RT-NH2 is fairly hydrophobic and cannot distribute in the nucleus, which is a hallmark of protein binding for fluorescent probe.
    RT-NH2
  • HY-D2881D
    RB-PEG-COOH (MW 3400)
    RB-PEG-COOH (MW 3400) (Rhodamine B-PEG-COOH (MW 3400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 3400) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm).
    RB-PEG-COOH (MW 3400)
  • HY-NP164A
    Concanavalin A-Cy5.5
    Concanavalin A-Cy5.5 (Con A-Cy5.5) is a Cy5.5 (HY-D0924)-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca2+/Mn2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins.
    Concanavalin A-Cy5.5
Cat. No. Product Name / Synonyms Application Reactivity