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  3. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D1515
    FM1-84
    98.92%
    FM1-84 (Neurodye GH1-84) is a fluorescent dye. FM1-84 has lipophilic and facilitates association with membranes, resulting in an increase in fluorescence intensity (λex=510 nm, λem=625 nm). FM1-84 can be used for synaptic vesicle recycling in neurons research.
    FM1-84
  • HY-D0078
    DCIA
    DCIA is a fluorescent dye. DCIA contains a coumarin fluorophore and conjugates specifically with free cysteines in the protein.
    DCIA
  • HY-P4417
    Ac-IEPD-AMC
    Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal.
    Ac-IEPD-AMC
  • HY-D0141
    12-(1-Pyrenyl)dodecanoic acid
    ≥98.0%
    12-(1-Pyrenyl)dodecanoic acid is a fluorescence probe.
    12-(1-Pyrenyl)dodecanoic acid
  • HY-W039519
    7-Methoxycoumarin-3-carboxylic acid
    7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide.
    7-Methoxycoumarin-3-carboxylic acid
  • HY-NP063
    Aleuria Aurantia Lectin
    Aleuria Aurantia Lectin (AAL) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Aleuria Aurantia Lectin (AAL) is a biological material or organic compound that can be used in life science research.
    Aleuria Aurantia Lectin
  • HY-101013
    D-SNAP
    D-SNAP (S-Nitroso-N-acetylpenicillamine) can Generate nitric oxide and form superoxides spontaneously under physiological conditions and is often used to probe the cell stress response and stimulate calcium-independent synaptic vesicle release.
    D-SNAP
  • HY-121986
    Yellow AB
    99.45%
    Yellow AB (Solvent yellow 5) is an azo dye that can be used as food dye.
    Yellow AB
  • HY-137099
    Genistein 7-sulfate
    Genistein 7-sulfate is a metabolite of genistein that can reduce the activity of estrogen agonists in MCF-7 cells. Genistein 7-sulfate can promote the growth of MCF-7 cells at concentrations of 10 μM and above.
    Genistein 7-sulfate
  • HY-D1635
    Sulfo-NHS-LC-LC-Biotin
    99.30%
    Sulfo-NHS-LC-LC-Biotin (Biotin-XX-SSE), a biotin reagent, is used to label the proteins exposed to the external leaflet of intact exosomes and contains a larger spacer arm between the biotin and amine reactive linker. The size of this linker helps to overcome steric hindrance and increases labeling efficiency at the crowded exosome surface.
    Sulfo-NHS-LC-LC-Biotin
  • HY-136405
    Melanin probe-2
    99.44%
    Melanin probe-2 (compound 5) is a non-radioactive bromopicolinamide precursor. Melanin probe-2 can be used for 18F-Labeled Picolinamide PET probe synthesis (HY-136404).
    Melanin probe-2
  • HY-131933
    DCP-Bio3
    98.10%
    DCP-Bio3 is a biotinylated probe that can detect labeled proteins in polyacrylamide gels. DCP-Bio3 can be used in research for the identification of oxidized and modified proteins.
    DCP-Bio3
  • HY-W248583
    Pyrromethene 650
    Pyrromethene 650 (PM650) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
    Pyrromethene 650
  • HY-D0929
    Orange I
    Orange I (α-Naphthol Orange) is an azo dye that can form a complex with Methylene blue (HY-14536) and cause fluorescence quenching. The equilibrium constant of the complex of Orange I and Methylene blue is 79900 mol-1·dm3. Orange I can change the absorption spectrum of itself and Methylene blue.
    Orange I
  • HY-D2106
    TAMRA-PEG4-NHS
    TAMRA-PEG4-NHS is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-NHS contains NHS groups that react with ammonia to form ester bonds.
    TAMRA-PEG4-NHS
  • HY-D0265
    Thymolphthalein
    99.85%
    Thymolphthalein is an electrochemically active dye due to the presence of thymol fragments. Thymolphthalein is a Phthalein dye used as an acid-base indicator. It is colourless in acid pH and is blue in basic pH.
    Thymolphthalein
  • HY-148835
    AzGGK
    99.51%
    AzGGK is an unnatural amino acid. AzGGK is site-specifically incorporated into proteins via genetic-code expansion. AzGGK can be used as site-specific probe for ubiquitylation and SUMOylation. AzGGK is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    AzGGK
  • HY-137333
    4-Methylumbelliferyl β-D-cellobioside
    99.43%
    4-Methylumbelliferyl β-D-cellobioside is a substrate of Cellulase (HY-B2220). 4-Methylumbelliferyl β-D-cellobioside can be hydrolyzed and produces fluorescent 4-methylumbelliferone, which can be used to study the kinetics of cellulases.
    4-Methylumbelliferyl β-D-cellobioside
  • HY-103305
    cis-Ned19
    99.25%
    cis-Ned19 is a chemical probe. cis-Ned19 blocks NAADP signaling and fluorescently labeled NAADP receptors in cell.
    cis-Ned19
  • HY-W442295
    Dipyrrometheneboron difluoride
    Dipyrrometheneboron difluoride is a green-fluorescent dye used for labeling nonpolar lipids and detecting calcium.
    Dipyrrometheneboron difluoride
Cat. No. Product Name / Synonyms Application Reactivity