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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D0281
    Pigment Yellow 14
    Pigment Yellow 14 is a fluorescent dye.
    Pigment Yellow 14
  • HY-D1798
    Vari Fluor 350 SE
    Vari Fluor 350 SE (VF 350 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=350 nm/448 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
    Vari Fluor 350 SE
  • HY-128536
    KMG-104AM
    KMG-104AM, a selective fluorescein-derived magnesium fluorescent membrane-permeable probe, successfully incorporates into PC12 cells and is used to Intracellular 3D Mg2+ Imaging .
    KMG-104AM
  • HY-D1629
    Calcium Orange AM
    Calcium Orange AM is an intracellular calcium reporter. Specific fluorescence can be detected when free calcium binds to Calcium Orange AM (Ex/Em=549/576 nm). Calcium Orange AM does not enter the vacuoles and does not compartmentalize into acidic vesicles.
    Calcium Orange AM
  • HY-P4419
    Boc-Asp(OBzl)-Pro-Arg-AMC
    Boc-Asp(OBzl)-Pro-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). The excitation and emission wavelengths are 351 nm and 430 nm, respectively.
    Boc-Asp(OBzl)-Pro-Arg-AMC
  • HY-W440914B
    DSPE-PEG-FITC (MW 10000)
    DSPE-PEG-FITC (MW 10000) is an amphiphile PEG polymer which has unsaturated lipid tails. DSPE-PEG-FITC (MW 10000) can form micelles in an aqueous solution and can be used to prepare liposome/nano particles for drug nanocarriers.
    DSPE-PEG-FITC (MW 10000)
  • HY-D1478
    Fluorescent polyamine probe-1
    Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe with high uptake efficiency. Fluorescent polyamine probe-1 can be used for the research of transport system into cancer cells.
    Fluorescent polyamine probe-1
  • HY-D2264
    Caffeine orange
    Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices.
    Caffeine orange
  • HY-D0920
    TOTO-3
    TOTO-3 (TOTO 3) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    TOTO-3
  • HY-149203
    MQA-P
    MQA-P is a multifunctional near-infrared (NIR) fluorescent probe for simultaneously detecting ONOO-, viscosity, and polarity within mitochondria. MQA-P exhibits a remarkable turn-on response to ONOO- (λem=645 nm) and is highly sensitive to viscosity/polarity in the NIR channel with λem>704 nm. MQA-P exhibits excited-state intramolecular charge transfer (ESICT) feature that is highly polarity-sensitive by engineering N,N-dimethylamino as the electron donor and a quinoline cationic unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images.
    MQA-P
  • HY-P0136AF
    FAM-SAMS TFA
    FAM-SAMS TFA is a 5-FAM (HY-66022) labeled SAMS (HY-P0136). SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).
    FAM-SAMS TFA
  • HY-NP0135
    Lotus Tetragonolobus Lectin (Fluorescein)
    Lotus Tetragonolobus Lectin (LTL) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Lotus Tetragonolobus Lectin (LTL) Fluorescein is a biological material or organic compound that can be used in life science research.
    Lotus Tetragonolobus Lectin (Fluorescein)
  • HY-W879342
    ICG-Tetrazine
    ICG-Tetrazine is a fluorescent dye.
    ICG-Tetrazine
  • HY-W014018
    2,5-Diphenyloxazole
    		99.43%
    2,5-Diphenyloxazole (PPO; DPO; POP) is a fluorescence dye. 2,5-Diphenyloxazole can be used as a scintillator.
    2,5-Diphenyloxazole
  • HY-135414
    Cyanine5 NHS ester chloride
    Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides.
    Cyanine5 NHS ester chloride
  • HY-D1577
    C6 NBD Lactosylceramide
    		≥98.0%
    C6 NBD Lactosylceramide is a derivative of lactosylceramides, and can be used in lactosylceramide synthase assay as a fluorescent acceptor substrate. C6 NBD Lactosylceramide can also be used in cancer research.
    C6 NBD Lactosylceramide
  • HY-140509
    TAMRA-PEG4-acid
    TAMRA-PEG4-acid is a dye derivative of TAMRA (HY-135640) containing 3 PEG units.
    TAMRA-PEG4-acid
  • HY-P5354
    FRETS-VWF73
    FRETS-VWF73, a 73-amino-acid peptide, is a fluorogenic substrate for ADAMTS13 assay (Ex=340 nm; Em=450 nm)..
    FRETS-VWF73
  • HY-D2161
    AF 594 azide
    AF 594 azide is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne). It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    AF 594 azide
  • HY-D0059
    4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride
    		≥98.0%
    4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) is a fluorescent labeling reagent. 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride can be used for labeling amines and successfully being applied to determine activator amines by HPLC.
    4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride
Cat. No. Product Name / Synonyms Application Reactivity