2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W088089
    ICG-carboxylic acid
    		99.85%
    ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue.
    ICG-carboxylic acid
  • HY-D0211
    Phenolphthalein
    		99.92%
    Phenolphthalein is an acid-base indicator that is colorless in an acidic environment and pink in an alkaline environment. Phenolphthalein is genotoxic and potentially carcinogenic to mice. In addition, phenolphthalein is also a blood indicator.
    Phenolphthalein
  • HY-117095
    4-Methylumbelliferyl oleate
    		99.68%
    4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline lipases. 4-Methylumbelliferyl oleate is cleaved by lipases, liberating 4-Methylumbelliferyl (Ex/Em=320/450 nm).
    4-Methylumbelliferyl oleate
  • HY-D1627
    CellTracker CM-DiI
    		≥98.0%
    CellTracker CM-DiI (CM-DiI) is a lipophilic fluorochrome that can be used for tracking the migration of lymphocytes. CellTracker CM-DiI is feasible to detect labeled cells in histological sections (excitation 553 nm; emission 570 nm).
    CellTracker CM-DiI
  • HY-158082A
    TRITC-dextran, MW 20000
    TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching.
    TRITC-dextran, MW 20000
  • HY-129042
    Cibacron Blue 3G-A
    Cibacron Blue 3G-A is an anthraquinone dye, inhibits the R46 β-lactamase with a Ki value of 1.2 uM.
    Cibacron Blue 3G-A
  • HY-D1296
    Green DND-26
    		98.95%
    Green DND-26 is a green fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 504/511 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and generally gather on spherical organelles. Green DND-26 is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes.
    Green DND-26
  • HY-D1341
    Coumberone
    		99.95%
    Coumberone is a metabolic fluorogenic probe, and isoform-selective substrate for all AKR1C isoforms. Coumberone can be reduced by all four members of the AKR1C family to its fluorescent alcohol coumberol. Coumberone can be used for the research of AKR1C.
    Coumberone
  • HY-P3236
    N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide
    		99.68%
    N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a granzyme B substrate that allows accurate measurement of granzyme B activity.
    N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide
  • HY-15938
    5-FAM SE
    5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates.
    5-FAM SE
  • HY-15909
    BCIP
    		99.93%
    BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity.
    BCIP
  • HY-D0981
    7-Amino-4-(trifluoromethyl)coumarin
    		99.30%
    7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a fluorescent marker for the sensitive detection of proteinases. The excitation and emission wavelengths are 400 and 490 nm, respectively.
    7-Amino-4-(trifluoromethyl)coumarin
  • HY-47176
    QTZ
    QTZ is a bioluminescence agent for in vivo imaging. QTZ has red-shifted emission and yields very little background. QTZ is a coelenterazine analog with the 4-quinolinyl substitution at the C8 position of the imidazopyrazinone core.
    QTZ
  • HY-D2295
    Mito-FerroGreen
    Mito-FerroGreen is a mitochondria-specific ferrous ion detection probe with an excitation wavelength of 488nm.
    Mito-FerroGreen
  • HY-114353
    BDP FL azide
    		99.71%
    BDP FL azide is a BDP dye connector containing an azide group capable of Click Chemistry. The green fluorophore is representative of the borodipyrromethane class of fluorescent dyes and has a high quantum yield in aqueous environments, high stability to photobleaching and is compatible with FAM fluorescence measurement instruments.
    BDP FL azide
  • HY-140296
    BDP FL DBCO
    		98.86%
    BDP FL DBCO is a photostable boron dipyrromethene used in the FAM (fluorescein) channel, with compatible property for fluorescein filters. BDP FL DBCO contains DBCO (azadibenzocyclooctyne) groups that enable copper-free catalyzed click chemistry reactions with azides. λex/λem= 503 nm/512 nm.
    BDP FL DBCO
  • HY-141729
    Biotin-NH-PSMA-617
    		98.77%
    Biotin-NH-PSMA-617 is a biotin-tagged PSMA-617. PSMA-617 is a small molecule targeting the prostate-specific membrane antigen (PSMA), which is directly expressed by the tumor cells .
    Biotin-NH-PSMA-617
  • HY-D1176
    Calcium Green 1AM
    Calcium Green 1AM is a cell-permeant fluorescent calcium indicator (Excitation 506 nm; Emission 531 nm). Calcium Green 1AM is converted to the fluorescent calcium indicator by intracellular esterases.
    Calcium Green 1AM
  • HY-153231
    eGFP mRNA-LNP
    eGFP mRNA-LNP is a lipid nanoparticle (LNP) containing eGFP mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry.
    eGFP mRNA-LNP
  • HY-130025
    HKOCl-3
    		99.51%
    HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid.Ex: 490 nm; Em 527 nm.
    HKOCl-3
Cat. No. Product Name / Synonyms Application Reactivity