2. Signaling Pathways
  3. Anti-infection
  4. Flavivirus

Flavivirus

Flavivirus

Flavivirus is a group of single-stranded positive-sense RNA viruses that are mainly transmitted by arthropods such as mosquitoes and ticks. The viral particles of the Flavivirus are spherical, with a diameter of approximately 40-60 nanometers and have an envelope. The envelope is embedded with spike glycoproteins, which play a crucial role in the recognition and binding process between the virus and host cells. Flavivirus contains a variety of viruses, such as the yellow fever virus and the dengue virus, etc., which can cause a variety of serious diseases and have a significant impact on global public health security[1].

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D0143R
    Quinine (Standard)
    Quinine (Standard) is the analytical standard of Quinine. This product is intended for research and analytical applications. Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
    Quinine (Standard)
  • HY-157023
    RCB16007
    		Inhibitor
    RCB16007 is a Yellow Fever Virus (YFV) Inhibitor. RCB16007 inhibits the West Nile virus (EC50: 7.9 μM, CC50: 17 μM).
    RCB16007
  • HY-161805
    GNF-2-acid
    		Inhibitor
    GNF-2-acid is a target protein ligand activity control that can be used for the synthesis of PROTACs (HY-161806) .
    GNF-2-acid
  • HY-163088
    CHIKV-IN-4
    		Inhibitor
    CHIKV-IN-4 (compound 31b) is a potent and selective CHIKV inhibitor. CHIKV-IN-4 inhibits the Chikungunya virus with the EC50 value of 0.6 μM.
    CHIKV-IN-4
  • HY-17043S3
    Loratadine-13C6
    Loratadine-13C6 (SCH 29851-13C6) is 13C labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.
    Loratadine-<sup>13</sup>C<sub>6</sub>
  • HY-124224
    D4-Ribavirin
    		Inhibitor
    D4-Ribavirin (Compound 4) is a deoxygenated ribavirin analogue. D4-Ribavirin has antiviral property in vitro against the RNA-containing bunyaviruses–Rift Valley Fever () with an IC50 of 61 μg/mL.
    D4-Ribavirin
  • HY-163132
    DDABT1
    DDABT1 has anti-CHIKV activity (IC50 of 14.53 μM) and the ability to reduce inflammation and arthritis.
    DDABT1
  • HY-10396R
    Emricasan (Standard)
    		Inhibitor
    Emricasan (Standard) is the analytical standard of Emricasan. This product is intended for research and analytical applications. Emricasan (PF 03491390) is an orally active and irreversible pan-caspase inhibitor. Emricasan inhibits Zika virus (ZIKV)-induced increases in caspase-3 activity and protected human cortical neural progenitors.
    Emricasan (Standard)
Cat. No. Product Name / Synonyms Application Reactivity