2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Factor VIII
  5. Factor VIII Inhibitor

Factor VIII Inhibitor

Factor VIII Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-162654
    FXIIIa-IN-1
    		Inhibitor
    FXIIIa-IN-1 (Compound 16) is a potent and selective FXIIIa (Factor XIIIa) inhibitor with an IC50 value of 2.4 μM. FXIIIa-IN-1 inhibits FXIIIa by competing with the Gln-donor protein substrate (dimethylcasein). FXIIIa-IN-1 holds promise for the development of effective and safe novel anticoagulants.
  • HY-P991516
    TB-402
    		Inhibitor
    TB-402, a human IgG4 anticoagulant monoclonal antibody, is a partial Factor VIII inhibitor. TB-402 has a prolonged antithrombotic effect. TB-402 can be used for the prevention of venous thromboembolism (VTE) after total knee replacement (TKR).