2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1544):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-169830
    2-(Cyclohexylmethyl)-plumbagin
    2-(Cyclohexylmethyl)-plumbagin is a derivative of the naphthoquinone compound Plumbagin (HY-N1497). Under nutrient-deprived conditions, 2-(Cyclohexylmethyl)-plumbagin selectively exhibits cytotoxicity against PANC-1 human pancreatic cancer cells (PC50 = 0.11 µM) and reduces the phosphorylation of Akt and mTOR in PANC-1 cells. 2-(Cyclohexylmethyl)-plumbagin also induces apoptosis (Apoptosis) in PANC-1 cells at a concentration of 1 µM. Additionally, 2-(Cyclohexylmethyl)-plumbagin reduces tumor volume and weight in a xenograft MiaPaCa-2 pancreatic cancer mouse model.
    2-(Cyclohexylmethyl)-plumbagin
  • HY-172066
    3,4-Dimethoxymethcathinone hydrochloride
    3,4-Dimethoxymethcathinone hydrochloride is an analog of Mephedrone. Mephedrone is a cathinone compound.
    3,4-Dimethoxymethcathinone hydrochloride
  • HY-139264
    Cloniprazepam
    Cloniprazepam is a benzodiazepine.
    Cloniprazepam
  • HY-W408972
    PCPr hydrochloride
    PCPr (hydrochloride) is a compound derived from phencyclidine.
    PCPr hydrochloride
  • HY-169699
    2-Chloromethcathinone hydrochloride
    2-Chloromethcathinone hydrochloride is a cathinone.
    2-Chloromethcathinone hydrochloride
  • HY-169466
    5-Methoxy-N,N-dimethyltryptamine Nb-oxide
    5-Methoxy-N,N-dimethyltryptamine Nb-oxide is an indole alkaloid. 5-Methoxy-N,N-dimethyltryptamine Nb-oxide is the N-oxide form of 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT), which is a known psychoactive substance.
    5-Methoxy-N,N-dimethyltryptamine Nb-oxide
  • HY-157179
    WAY-312491
    		98.0%
    WAY-312491 is an active molecule.
    WAY-312491
  • HY-170049
    5-Chloro DMT hydrochloride
    5-chloro DMT (5-Chloro-N,N-dimethyltryptamine) hydrochloride is a Tryptamine (HY-B2132).
    5-Chloro DMT hydrochloride
  • HY-W721505
    4-Chloro-N-butylcathinone hydrochloride
    4-Chloro-N-butylcathinone hydrochloride is structurally categorized as a cathinone.
    4-Chloro-N-butylcathinone hydrochloride
  • HY-W750595
    6-(L-1,2,3-Trihydroxybutyl)-pterin
    6-(L-1,2,3-Trihydroxybutyl)-pterin is a derivative of L-biopterin (HY-102015) and is the oxidized form of tetrahydro-L-biopterin (BH4) as well as D-biopterin. Co-ingestion of 6-(L-1,2,3-Trihydroxybutyl)-pterin (0.5%) with the carcinogen 4-dimethylaminoazobenzene reduces the incidence of 4-dimethylaminoazobenzene-induced liver tumors in rats. 6-(L-1,2,3-Trihydroxybutyl)-pterin has been used as an internal standard for the LC-MS quantification of biopterin and neopterin in rat plasma.
    6-(L-1,2,3-Trihydroxybutyl)-pterin
  • HY-W750675
    Astaxanthin monopalmitate
    Astaxanthin monopalmitate (Astaxanthin palmitate) is an esterified form of Astaxanthin (HY-B2163) (a carotenoid). Astaxanthin monopalmitate degradation resulted in a mixture of free and palmitate apo-astaxanthins. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition.
    Astaxanthin monopalmitate
  • HY-171987
    trans-4-Hydroxyprolinol-C10-tri-GalNAc
    trans-4-Hydroxyprolinol-C10-tri-GalNAc (Formula XXIV) is a Tri-GaINAc derivative that can be used for nucleic acid drug coupling.
    trans-4-Hydroxyprolinol-C10-tri-GalNAc
  • HY-Y0004R
    2-Pyridinemethanol (Standard)
    2-Pyridinemethanol is a pyridylalcohol, with hypoglycemic activity.
    2-Pyridinemethanol (Standard)
  • HY-W010132
    5-Nitrobenzimidazole
    		99.74%
    5-nitrobenzimidazole is a genotoxic nitro compound and 6-aminopurine (HY-B0152) analogue. 5-nitrobenzimidazole shows a slight inhibitory effect on xanthine oxidase, with an IC50 of 86.84 μM. 5-nitrobenzimidazole can be used in the research of hyperuricemia.
    5-Nitrobenzimidazole
  • HY-149743
    WAY-606376
    		≥98.0%
    WAY-606376 is an active molecule.
    WAY-606376
  • HY-N15111
    Phosmidosine C
    Phosmidosine C is a phosmidosine derivative.
    Phosmidosine C
  • HY-W588234
    Pseudovardenafil
    Pseudovardenafil is a new Vardenafil (HY-B0442) analog illegally added to dietary supplements.
    Pseudovardenafil
  • HY-116948
    Azo-mustard
    Azo-mustard is a nitrogen mustard derivative with mutagenic effects in Drosophila melanogaster males.
    Azo-mustard
  • HY-173550
    Methyl α-Linolenyl Fluorophosphonate
    Methyl α-Linolenyl Fluorophosphonate (MLnFP) is an analog of Methyl arachidonyl fluorophosphonate (HY-103334). Methyl arachidonyl fluorophosphonate is an anandamide amidase inhibitor.
    Methyl α-Linolenyl Fluorophosphonate
  • HY-N7138R
    2-(Phosphonooxy)benzoic acid (Standard)
    2-(Phosphonooxy)benzoic acid is a non-acetylated salicylic acid derivative which has the potential for inflammatory disease as well as in analgesic therapy.
    2-(Phosphonooxy)benzoic acid (Standard)