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  3. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1537):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-124198
    2,1,3-Benzoselenadiazole
    2,1,3-Benzoselenadiazole is an active compound.
    2,1,3-Benzoselenadiazole
  • HY-100265
    Cinperene
    Cinperene is an atropine-like agent which can block pilocarpine-induced lacrimation and salivation.
    Cinperene
  • HY-169461
    Δ8-THCO
    Δ8-THCO (delta 8-tetrahydrocannabinol) is a cannabinoid compound that can be isolated from medicinal cannabis (sp. Sativa).
    Δ8-THCO
  • HY-115421
    11(R)-HEPE
    11(R)-HEPE is a monohydroxy fatty acid derived from EPA (eicosapentaenoic acid).
    11(R)-HEPE
  • HY-123197
    FR-193879
    FR-193879 is an active compound.
    FR-193879
  • HY-123529
    LY389795
    LY389795 is an active compound.
    LY389795
  • HY-N1631
    1-Hydroxyrutecarpine
    1-Hydroxyrutaecarpine (compound 1a) is a hydroxy-derivative of rutaecarpine. 1-Hydroxyrutaecarpine shows cytotoxicities with ED50s of 3.72, 7.44 µg/mL for P-388 and HT-29 cells, respectively. 1-Hydroxyrutaecarpine shows antiplatelet activity.
    1-Hydroxyrutecarpine
  • HY-108388
    Cloethocarb
    Cloethocarb is an active compound.
    Cloethocarb
  • HY-135076
    2,3-DMMC hydrochloride
    2,3-Dimethylmethcathinone hydrochloride is a cathinone analog.
    2,3-DMMC hydrochloride
  • HY-121543
    Sch 38548
    Sch 38548 is an active compound.
    Sch 38548
  • HY-101004
    PCA 4248
    PCA 4248 is an active compound.
    PCA 4248
  • HY-139030
    28-O-Acetylbetulin
    28-O-Acetylbetulin (Compound 4) is a derivative of Betulin (HY-N0083). 28-O-Acetylbetulin has anticancer activity.
    28-O-Acetylbetulin
  • HY-118182
    Tidembersat
    Tidembersat (Example 4) is a benzopyran derivative that can be used in the research of a variety of CNS disorders and traumatic brain injury.
    Tidembersat
  • HY-120313
    SN23862
    SN23862 is a cancer prodrug with anti-cancer activity, and an analogue of CB-1954 (HY-13543). SN23862 can be used for cancer research.
    SN23862
  • HY-N6657
    7-Hydroxy-4-methyl-8-nitrocoumarin
    99.71%
    7-Hydroxy-4-methyl-8-nitrocoumarin is a coumarin derivative.
    7-Hydroxy-4-methyl-8-nitrocoumarin
  • HY-115962
    Anticancer agent 37
    Anticancer agent 37 (compound 18), a sulfonylurea derivative, is a potent anticancer agent. Anticancer agent 37 inhibits HePG2 cell growth with an IC50 of 17.2 µg/mL.
    Anticancer agent 37
  • HY-111070
    Karavilagenin D
    Karavilagenin D, a cucurbitane-type triterpene isolated from Japanese bitter melon leaves, is a potential tumor-promoting inhibitor.
    Karavilagenin D
  • HY-19156
    ZD-6888
    ZD-6888 is an active compound.
    ZD-6888
  • HY-121146
    Chinotilin iodide
    Chinotilin (iodide) serves as an antagonist for muscle relaxation.
    Chinotilin iodide
  • HY-136630
    Felotaxel
    Felotaxel (SHR110008) is a derivate of Docetaxel (HY-B0011), with antitumor activity and specific pharmacokinetic properties in rats. Felotaxel is rapidly distributed to normal tissues. The kidney is the major excretion organ, and its plasma protein binding capacity is nearly linearly related to concentration.
    Felotaxel