2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1537):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-129672
    Thelenotoside B
    Thelenotoside B (25-Dihydrostichorrenoside E) shows strong cytotoxicities against five cancer cell lines as HepG2, KB, LNCaP, MCF7 and SK-Mel2 with the IC50 values from 0.95 ± 0.08 to 1.90 ± 0.13 μM. Thelenotoside B is a triterpene tetraglycoside.
    Thelenotoside B
  • HY-119140
    LY 116467
    LY 116467 is an active compound.
    LY 116467
  • HY-155039
    Antitumor agent-105
    Antitumor agent-105 (Compound 37) is an antitumor agent. Antitumor agent-105 has antitumor activity against A549, H1299, H460, HCT116, MDA-MB-231 cells, with IC50 values of 6.7, 8.3, 4.3, 4.4, 6.7 μM respectively.
    Antitumor agent-105
  • HY-49075
    WAY-622252
    		98.0%
    WAY-622252 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-622252
  • HY-129513
    SIB-1893
    SIB-1893 is an active compound.
    SIB-1893
  • HY-118464
    AC915
    AC915 is an active compound.
    AC915
  • HY-49458
    WAY-232897
    		98.0%
    WAY-232897 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-232897
  • HY-175085
    17-Phenyl trinor 8-iso prostaglandin E2
    17-Phenyl trinor 8-iso prostaglandin E2 is a prostaglandin analog that reduces intraocular pressure (IOP) in both normal and glaucomatous monkey eyes. 17-Phenyl trinor 8-iso prostaglandin E2 lowers IOP primarily by increasing trabecular outflow facility.
    17-Phenyl trinor 8-iso prostaglandin E2
  • HY-167931
    Cinnamohydrazide
    Cinnamohydrazide, an unsaturated carboxylic acid derivative, serves as a precursor to aspartame through enzyme-mediated amination to phenylalanine. This compound may offer potential benefits in the prevention and treatment of diabetes by facilitating insulin secretion, enhancing pancreatic β-cell function, inhibiting hepatic gluconeogenesis, promoting glucose uptake, amplifying insulin signaling pathways, delaying carbohydrate digestion and glucose absorption, and reducing protein glycation and insulin fibrillation.
    Cinnamohydrazide
  • HY-133607
    5,6-Dichlorovanillin
    5,6-Dichlorovanillin is a product upon chlorination to afford 4,5,6-trichloroguaiacol, together with tetrachloroguaiacol and the unreacted starting materials.
    5,6-Dichlorovanillin
  • HY-117984
    RU 35929
    RU 35929 is a nootropic agent. RU 35929 enhances learning and memory.
    RU 35929
  • HY-121436
    Levoxadrol
    Levoxadrol is an active enantiomer of dexoxadrol.
    Levoxadrol
  • HY-129796
    3'-Fluoroaminopterin
    3'-Fluoroaminopterin is an active compound.
    3'-Fluoroaminopterin
  • HY-P11111
    QP5
    QP5 is an Amelogenin (HY-P71627)-derived peptide. QP5 binds on the hydroxyapatite and demineralized tooth enamel surfaces, transitorily stabilize the amorphous calcium phosphate (ACP), control the crystallization of hydroxyapatite and promote the remineralization of caries lesions. QP5 promotes remineralization in rat caries models. QP5 can be used for oral diseases like dental caries research.
    QP5
  • HY-119755
    Quadrosilan
    Quadrosilan is an active compound.
    Quadrosilan
  • HY-123555
    PD 142505-0028
    PD 142505-0028 is an active compound.
    PD 142505-0028
  • HY-119113
    C 175
    C 175 is a nitroacridine derivative with antitumor activity. C 175 inhibits the growth of HeLa cells monolayer (ED50=0.49 μM).
    C 175
  • HY-155755
    CES2A-IN-1
    CES2A-IN-1 (compound 20w) is a potent CES2A inhibitor with an IC50 value of 1.6 nM for human CES2A. CES2A-IN-1, a bysspectin A derivative, shows an approximately 1000-fold improvement over the lead compound bysspectin A.
    CES2A-IN-1
  • HY-165141
    (+)-Anominine
    (+)-Anominine is an active compound.
    (+)-Anominine
  • HY-118354
    A 80556
    A 80556 is an active compound.
    A 80556