2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1537):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-176159
    3,4-Dimethylene-α-pyrrolidinovalerophenone hydrochloride
    3,4-Dimethylene-α-pyrrolidinovalerophenone (3,4-EtPV) hydrochloride is a psychoactive substance belonging to the cathinone class.
    3,4-Dimethylene-α-pyrrolidinovalerophenone hydrochloride
  • HY-111761
    DIQ3
    DIQ3 is a potent anti-cancer agent, nontoxic to normal human cell lines.
    DIQ3
  • HY-120768
    A-30312
    A-30312 is a compound that can overcome multidrug resistance and has the activity of reversing multidrug resistance. A-30312 can enhance the cytotoxicity of antitumor compounds in multidrug-resistant cells, increase the accumulation of compounds in cells, inhibit the efflux of compounds, and compared with calcium antagonists, it has no serious hypotensive effect. Its activity may be unrelated to the ability to block calcium transport.
    A-30312
  • HY-116137
    Nav1.7-IN-17
    Nav1.7-IN-17 is an active compound.
    Nav1.7-IN-17
  • HY-N15715
    Acoraminol B
    Acoraminol B is one of the stereoisomers of phenylpropanoids, the other of which is Acoraminol A (HY-N15714), which can be isolated from the methanol extract of the rhizome of Acorus tatarinowii. Acoraminol B has weak cytotoxic effects on several human tumor cell lines (IC50>30 μM).
    Acoraminol B
  • HY-111203
    TT-301
    TT-301 is an active compound.
    TT-301
  • HY-134048
    Erucoylcarnitine
    Erucoylcarnitine is an active compound.
    Erucoylcarnitine
  • HY-124926
    S23757
    S23757 is an active compound.
    S23757
  • HY-129954
    6-EAPB hydrochloride
    6-EAPB hydrochloride is a benzofuran.
    6-EAPB hydrochloride
  • HY-120719
    SB 201823-A
    SB 201823-A is an active compound.
    SB 201823-A
  • HY-120198
    Naftypramide
    Naftypramide is an active compound.
    Naftypramide
  • HY-176049
    Dasatinib derivative 1
    Dasatinib derivative 1 (2e) effectively releases NO and increases the concentration of 3′,5′-cyclic guanosine monophosphate, as well as maintains senolytic activity. Dasatinib derivative 1 (2e) can be used in the research for chronic ocular hypertension (COHT) glaucoma.
    Dasatinib derivative 1
  • HY-120410A
    DL-4662 hydrochloride
    DL-4662 hydrochloride is a psychoactive substance and belongs to cathinone derivatives.
    DL-4662 hydrochloride
  • HY-N15555
    Thaigranatumin B
    Thaigranatumin B is a protolimonoid compound found in the seeds of the Thai mangrove (Xylocarpus granatum). Thaigranatumin B is promising for research of neurodegenerative diseases such as Parkinson's diseases.
    Thaigranatumin B
  • HY-112580
    SRI-31040
    SRI-31040 is an active compound.
    SRI-31040
  • HY-47601
    WAY-637940
    		98.0%
    WAY-637940 is an active molecule.
    WAY-637940
  • HY-119885
    Amiflamine
    Amiflamine is an active compound.
    Amiflamine
  • HY-139090
    3-Oxobetulin acetate
    3-Oxobetulin acetate (28-O-Acetyl-3-Oxobetulin; 3-oxo-28-O-Acetylbetulin) is a derivative of betulin (HY-N0083), a cholesterol biosynthesis inhibitor. 3-Oxobetulin acetate inhibits the growth of P388 murine lymphocytic leukemia cells (EC50=0.12 μg/mL) and human MCF-7 breast cancer, SF-268 CNS cancer, H460 lung cancer, and KM20L2 colon cancer cells (GI50s=8, 10.6, 5.2, and 12.7 μg/mL), but not BxPC-3 pancreatic cancer cells or DU145 prostate cancer cells (GI50s=>10 μg/mL for both). 3-Oxobetulin acetate inhibits the replication of X4-tropic recombinant HIV (NL4.3-Ren) in MT-2 lymphoblastoid cells (IC50=13.4 μM). 3-Oxobetulin acetate is also effective against Listeria donovani amastigotes.
    3-Oxobetulin acetate
  • HY-148960
    Bis(diazoacetyl)butane
    Bis(diazoacetyl)butane is an active compound.
    Bis(diazoacetyl)butane
  • HY-135060
    3,4-DCMC hydrochloride
    3,4-Dichloromethcathinone hydrochloride is a cathinone.
    3,4-DCMC hydrochloride