2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1537):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-119034
    AD-20
    AD-20 is an o-methoxyphenylacetyl dehydroalanine derivative. AD-20 can not only reduce the acute and subchronic toxicity of Doxorubicin (HY-15142A), but also enhance its anti-tumor effect.
    AD-20
  • HY-114561
    LY 97119
    LY 97119 is an active compound.
    LY 97119
  • HY-123157
    Methoserpidine
    Methoserpidine is an active compound.
    Methoserpidine
  • HY-119899
    BO-0742
    BO-0742, a derivative of AHMA and N-mustard, is a potent anti-cancer agent. BO-0742 significantly suppresses the growth of xenografts of human breast and ovarian cancers in mice.
    BO-0742
  • HY-115995
    Antitumor agent-50
    Antitumor agent-50 (compound 1a), a thiazolidinone, is a potent antitumor agent. Antitumor agent-50 has the potential for osteosarcoma (OS) research.
    Antitumor agent-50
  • HY-172748
    9β-Hydroxyhexahydrocannabinol
    9β-Hydroxyhexahydrocannabinol is a synthetic cannabinoid derivative. 9β-Hydroxyhexahydrocannabinol exhibits cytotoxicity against various tumor cell lines, such as HCT-116, MCF-7, K562, MIAPaCa-2, PANC-1, A549, PC-3 and SW-620, with IC50 values ranging from 15.23 to 33.74 μM. 9β-Hydroxyhexahydrocannabinol can be used in the study of cancer.
    9β-Hydroxyhexahydrocannabinol
  • HY-138146
    4-Dehydrowithaferin A
    4-Dehydrowithaferin A is the analogue of withaferin A. Withaferin A is a withanolide isolated from Withania somnifera. 4-Dehydrowithaferin A has the potential for the research of multiple myeloma.
    4-Dehydrowithaferin A
  • HY-131171
    3β,5α-Tetrahydronorethisterone
    3β,5α-Tetrahydronorethisterone is a tetrahydro derivative of norethindrone (NET).
    3β,5α-Tetrahydronorethisterone
  • HY-168357
    Cannabiphorol
    Cannabiphorol (compound 4d) is a rare cannabinoid closely related to cannabinol. Cannabiphorol has the potential for the research of synergistic effects when combined with other cannabinoids.
    Cannabiphorol
  • HY-107219
    Jatropholone B
    Jatropholone B is a jatrophone derivative that can be isolated fromJatropha isabelliand has certain gastric protective effects.
    Jatropholone B
  • HY-W726084
    1,2:5,6-Di-O-isopropylidene-L-chiro-inositol
    1,2:5,6-Di-O-isopropylidene-L-chiro-inositol is a derivative of inositol.
    1,2:5,6-Di-O-isopropylidene-L-chiro-inositol
  • HY-171798
    BAM-2101
    BAM-2101 is an ergoline derivative with antihypertensive activity. BAM-2101 is orally active and lowers blood pressure in spontaneously hypertensive rats.
    BAM-2101
  • HY-108996
    PD 118879
    PD 118879 is an active compound.
    PD 118879
  • HY-168014
    5-Methylthio DMT
    5-Methylthio DMT (5-OMe DMT) is a tryptamine with psychoactivity.
    5-Methylthio DMT
  • HY-113755
    AA-1777
    AA-1777 is an active compound.
    AA-1777
  • HY-135378
    Atorvastatin ethyl ester
    		98.16%
    Atorvastatin ethyl ester is a derivative of Atorvastatin and displays strong inhibition of the 9-cis-RA-induced Gal4 reporter activity.
    Atorvastatin ethyl ester
  • HY-158004
    SMU101
    SMU101 is an active compound.
    SMU101
  • HY-114198
    Tenovin-2
    Tenovin-2 is an active compound.
    Tenovin-2
  • HY-47634
    WAY-658675
    		98.0%
    WAY-658675 is an active molecule.
    WAY-658675
  • HY-175861
    NSC20116
    NSC20116 is a uracil derivative that specifically targets the Set-and-Ring (SRA) domain of the oncogene UHRF1. NSC20116 binds to the 5-methylcytosine (5mC) (HY-W008091) recognition pocket of UHRF1 SRA domain, with a dissociation constant (Kd) of 362 nM. NSC20116 can be used for the study of cancer.
    NSC20116