2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1534):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-114002
    Anticancer agent 129
    		99.01%
    Anticancer agent 129 (Compound 3a), a quinoline derivative, predicting to has anti-cancer activity.
    Anticancer agent 129
  • HY-172337
    Fluorexetamine hydrochloride
    Fluorexetamine (3-Fluoro-2-oxo PCE) hydrochloride is a fluorinated β-ketoarylcyclohexylamine.
    Fluorexetamine hydrochloride
  • HY-122043
    Nimolinone
    Nimolinone is an active compound.
    Nimolinone
  • HY-106809
    BMY-21502
    BMY-21502 (BMS-181168) is a pyrrolidinone derivative with memory- and cognition-enhancing activities. BMS-181168 attenuates hypoxia-induced deterioration in brain function, as delta/theta decreases, alpha activity increases and the centroid of the combined delta/theta waves is accelerated.
    BMY-21502
  • HY-126582
    Reprimun
    Reprimun is an active compound.
    Reprimun
  • HY-107008
    SW 71425
    SW 71425 inhibits cell growth against breast, colon, non-small cell lung, and ovarian tumors..
    SW 71425
  • HY-173534
    Arachidonic acid sulfonate sodium
    Arachidonic acid sulfonate (AA sulfonate) sodium is a derivative of Arachidonic acid (HY-109590) containing a sulfonate group.
    Arachidonic acid sulfonate sodium
  • HY-47600
    WAY-323756
    		98.0%
    WAY-323756 is an active molecule for research into amyloid diseases and synucleinopathies.
    WAY-323756
  • HY-121934
    BH3I-2'
    BH3I-2' is the BH3I-2 analogue. BH3I-2 is a Bcl-2 family inhibitor. BH3I-2' can be used for various studies.
    BH3I-2'
  • HY-121307
    Gliamilide
    Gliamilide is an active and well tolerated sulfamylurea derivative and displays a very short plasma half-life. Gliamilide is promising for research of maturity-onset diabetic deseases.
    Gliamilide
  • HY-115850
    Ornithine-methotrexate
    Ornithine-methotrexate is an active compound.
    Ornithine-methotrexate
  • HY-133649
    Dibromochloroacetaldehyde
    Dibromochloroacetaldehyde belongs to trihalogenated acetaldehyde and is a byproduct in drinking water. Dibromochloroacetaldehyde has genotoxicity.
    Dibromochloroacetaldehyde
  • HY-122084
    (3β,5α)-Androstan-3-amine hydrochloride
    (3β,5α)-Androstan-3-amine (hydrochloride) is an active compound.
    (3β,5α)-Androstan-3-amine hydrochloride
  • HY-N15714
    Acoraminol A
    Acoraminol A is one of the stereoisomers of phenylpropanoids, the other of which is Acoraminol B (HY-N15715), which can be isolated from the methanol extract of the rhizome of Acorus tatarinowii. Acoraminol A has weak cytotoxic effects on several human tumor cell lines (IC50>30 μM).
    Acoraminol A
  • HY-123168
    ZIMET 124/73
    ZIMET 124/73 is a hetarylhydrazone derivative. ZIMET 124/73 is a potent antiviral agent. ZIMET 124/73 can be used for Mengo virus research.
    ZIMET 124/73
  • HY-W050088S
    Isoxepac-d6
    Isoxepac-d6 (HP 549-d6) is the deuterium labeled Isoxepac (HY-W050088). Isoxepac (HP 549) is an orally active non-steroidal anti-inflammatory agent. Isoxepac can inhibit Carrageenan (HY-125474) paw oedema, adjuvant-induced polyarthritis, and prostaglandin synthesis. Isoxepac (200 mg) has an analgesic effect after meniscectomy with a low incidence of side effects. Isoxepac can be used in the research of inflammatory (rheumatoid arthritis) and pain-related diseases.
    Isoxepac-d<sub>6</sub>
  • HY-W141863
    DL-Methionine Sulfone
    DL-Methionine Sulfone is a Methionine (HY-13694) derivative.
    DL-Methionine Sulfone
  • HY-156879
    Antiproliferative agent-40
    Antiproliferative agent-40 (Compound 9) inhibits proliferation of HT1080 and MCF-7 with IC50s of 52 and 8.2 μM respectively.
    Antiproliferative agent-40
  • HY-120043
    KCO912
    KCO912 is an active compound.
    KCO912
  • HY-118499
    Alpiropride
    Alpiropride (RIV-2093) is a metoclopramide (HY-17382) analog that is effective in reducing the gastrointestinal side effects of cancer chemotherapy drugs. In animal studies, alpiropride showed a stronger antiemetic effect than metoclopramide.
    Alpiropride